Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Invasive fungal infections (IFIs) represent a severe complication of COVID-19, yet they are under-estimated. We conducted a retrospective analysis including all the COVID-19 patients admitted to the Infectious Diseases Unit of the Federico II University Hospital of Naples until the 1 July 2021. Among 409 patients, we reported seven cases of IFIs by Candida spp., seven of Pneumocystis jirovecii pneumonia, three of invasive pulmonary aspergillosis, and one of Trichosporon asahii. None of the cases presented underlying predisposing conditions, excluding one oncohematological patient treated with rituximab. Ten cases showed lymphopenia with high rates of CD4+ < 200/µL. All cases received high-dose steroid therapy (mean duration 33 days, mean cumulative dosage 1015 mg of prednisone equivalent), and seven cases had severe COVID-19 disease (OSCI ≥ 5) prior to IFI diagnosis. The cases showed a higher overall duration of hospitalization (63 vs 24 days) and higher mortality rate (23% vs. 7%) compared with the COVID-19 patients who did not developed IFIs. Cases showed a higher prevalence of high-dose steroid therapy and lymphopenia with CD4+ < 200/µL, primarily due to SARS-CoV-2 infection and not related to underlying comorbidities. IFIs strongly impact the overall length of hospitalization and mortality. Therefore, clinicians should maintain a high degree of suspicion of IFIs, especially in severe COVID-19 patients.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865967 | PMC |
| http://dx.doi.org/10.3390/jof9010086 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Future-Proofing European Pharmaceutical Regulatory and Market Access Practices Based on EU Learnings from the COVID-19 Pandemic: Insights from Multi-Stakeholder Interviews.
Ther Innov Regul Sci
September 2025
Clinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Introduction: During the COVID-19 pandemic, regulatory and market access actions were taken to expedite the market entry of COVID-19 medicines. This study aims to (i) capture multi-stakeholder views on these actions, and (ii) provide recommendations for future-proofing routine and health-emergency frameworks.
Methods: Semi-structured interviews were conducted with policy makers/advisors (i.
Older Subjects Admitted to Hospital With Stroke From Long-Term Care: A National Cohort and Case Control Study.
J Am Med Dir Assoc
September 2025
Irish National Audit of Stroke Care, National Office of Clinical Audit, Dublin, Ireland; St Vincent's University Hospital, Dublin, Ireland.
Objectives: Internationally about 3% of people ≥65 years live in long-term care (LTC) settings. Older people living in nursing homes are more likely to be admitted to hospital. We examined the characteristics and outcomes of stroke patients admitted from LTC nationally and how this changed over the COVID-19 pandemic.
View Article and Find Full Text PDFIncidence of long COVID among U.S. children and adults during the omicron era - Tracking Post-COVID Conditions (Track-PCC) network, 2022-2023.
J Infect Public Health
August 2025
Centers for Disease Control and Prevention, National Center for Immunizations and Respiratory Diseases, Atlanta, GA, USA.
Background: Long COVID, or Post-COVID Conditions (PCC), refers to new and persisting sequelae occurring in the months following an acute SARS-CoV-2 infection. Although previous studies have reported estimates of PCC incidence, few have examined trends during the Omicron variant period or have included geographically distinct regions for the same time periods.
Methods: Track PCC is a surveillance network, leveraging electronic health records and public health data to monitor incidence over time across five diverse geographic sites in the U.
Medical and economic influence of the German hospital reform in 2024 on the hospitalisation and treatment of patients with odontogenic abscesses: the lessons learnt from the COVID-19 pandemic.
Br Dent J
September 2025
Managing Senior Physician, Department of Oral and Maxillofacial Surgery, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Introduction The COVID-19 pandemic significantly disrupted healthcare systems worldwide, including in Germany. This study investigated the impact of the pandemic on the management of dental abscesses and examined the implications for the upcoming German healthcare reform.Aims To assess how the COVID-19 pandemic affected hospitalisation, intensive care unit (ICU) admissions and treatment outcomes for dental abscesses, and to analyse the relationships between these findings and the German healthcare reform.
View Article and Find Full Text PDFDefining self-monitoring in postpandemic maternity care: Perspectives from women, partners, healthcare professionals, and policymakers.
Acta Obstet Gynecol Scand
September 2025
Department of Women & Children's Health, School of Life Course & Population Sciences, King's College London, London, UK.
Introduction: We aimed to explore the conceptualization and perception of self-monitoring amongst women, partners, healthcare professionals (HCPs), and policymakers, with particular interest in those living with social/medical complexity.
Material And Methods: Across the United Kingdom, 96 semi-structured in-depth qualitative interviews were conducted with 40 women, 15 partners, 21 HCPs, and 20 policymakers to discuss their lived experience of utilizing, delivering, or developing policy for self-monitoring during the COVID-19 pandemic. A thematic framework analysis was undertaken to develop themes, considered by participant type, ethnicity, geographical region, personal experience of self-monitoring, and social complexity, and a content analysis was used to explore how self-monitoring was conceptualized.