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Introduction The COVID-19 pandemic significantly disrupted healthcare systems worldwide, including in Germany. This study investigated the impact of the pandemic on the management of dental abscesses and examined the implications for the upcoming German healthcare reform.Aims To assess how the COVID-19 pandemic affected hospitalisation, intensive care unit (ICU) admissions and treatment outcomes for dental abscesses, and to analyse the relationships between these findings and the German healthcare reform.Design Retrospective cohort study.Setting A major metropolitan hospital in Munich.Materials and methods In total, 200 patients (93 in 2019, 107 in 2020) with dental abscesses were studied. Data collected included demographics, pre-hospitalisation antibiotic use, ICU admissions, and length of stay (LOS). Statistical analysis compared the outcomes between the two years.Results ICU LOS significantly decreased in 2020 (3.3 days versus 13.7 days in 2019; p = 0.022). More patients in 2020 received antibiotics before hospitalisation and fewer required surgeries. Overall, hospital resource usage was more efficient in 2020.Discussion The pandemic emphasised the importance of preventive dental care. It highlighted how local dental offices can play a more significant role in managing dental emergencies, with potential implications for the German healthcare system's future structure and resource allocation.Conclusion The COVID-19 pandemic reshaped dental emergency care and hospital resource usage. This shift has significant implications for the future organisation of healthcare, especially in the context of the German hospital reform.
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http://dx.doi.org/10.1038/s41415-025-8716-1 | DOI Listing |
BMC Health Serv Res
September 2025
Health Services Research, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
Infect Dis Ther
September 2025
School of Biomedical Sciences, The Chinese University of Hong Kong (CUHK), Hong Kong SAR, China.
Introduction: The high mortality of Coronavirus Disease 2019 (COVID-19) highlights the need for safe and effective antiviral treatment. Small molecular antivirals (remdesivir, molnupiravir, nirmatrelvir/ritonavir) and immunomodulators (baricitinib, tocilizumab) have been developed or repurposed to suppress viral replication and ameliorate cytokine storms, respectively. Despite U.
View Article and Find Full Text PDFNeurol Sci
September 2025
Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
The rapid evolution of digital tools in recent years after COVID-19 pandemic has transformed diagnostic and therapeutic practice in neurology. This shift has highlighted the urgent need to integrate digital competencies into the training of future specialists. Key innovations such as telemedicine, artificial intelligence, and wearable health technologies have become central to improving healthcare delivery and accessibility.
View Article and Find Full Text PDFAAPS PharmSciTech
September 2025
Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt.
The chimpanzee adenovirus-vectored vaccine developed by the University of Oxford (ChAdOx1 nCoV-19) showed good stability when stored in refrigerator. However, the vaccine manufacturer prefers its transportation in frozen condition. Data regarding the stability of the vaccine after exposure to repeated freezing processes have not been explored yet.
View Article and Find Full Text PDFMol Syst Biol
September 2025
Centre for Individualised Infection Medicine (CiiM), a joint venture between the Helmholtz Centre for Infection Research (HZI) and Hannover Medical School (MHH), Hannover, Germany.
The complex interplay between circulating metabolites and immune responses, which is pivotal to disease pathophysiology, remains poorly understood and understudied in systematic research. Here, we performed a comprehensive analysis of the immune response and circulating metabolome in two Western European cohorts (534 and 324 healthy individuals) and one from sub-Saharan Africa (323 healthy donors). At the metabolic level, our analysis revealed sex-specific differences in the correlation between phosphatidylcholine and cytokine responses following ex vivo stimulation.
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