98%
921
2 minutes
20
Diagnosing a brain tumor takes a long time and relies heavily on the radiologist's abilities and experience. The amount of data that must be handled has increased dramatically as the number of patients has increased, making old procedures both costly and ineffective. Many researchers investigated a variety of algorithms for detecting and classifying brain tumors that were both accurate and fast. Deep Learning (DL) approaches have recently been popular in developing automated systems capable of accurately diagnosing or segmenting brain tumors in less time. DL enables a pre-trained Convolutional Neural Network (CNN) model for medical images, specifically for classifying brain cancers. The proposed Brain Tumor Classification Model based on CNN (BCM-CNN) is a CNN hyperparameters optimization using an adaptive dynamic sine-cosine fitness grey wolf optimizer (ADSCFGWO) algorithm. There is an optimization of hyperparameters followed by a training model built with Inception-ResnetV2. The model employs commonly used pre-trained models (Inception-ResnetV2) to improve brain tumor diagnosis, and its output is a binary 0 or 1 (0: Normal, 1: Tumor). There are primarily two types of hyperparameters: (i) hyperparameters that determine the underlying network structure; (ii) a hyperparameter that is responsible for training the network. The ADSCFGWO algorithm draws from both the sine cosine and grey wolf algorithms in an adaptable framework that uses both algorithms' strengths. The experimental results show that the BCM-CNN as a classifier achieved the best results due to the enhancement of the CNN's performance by the CNN optimization's hyperparameters. The BCM-CNN has achieved 99.98% accuracy with the BRaTS 2021 Task 1 dataset.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854739 | PMC |
http://dx.doi.org/10.3390/bioengineering10010018 | DOI Listing |
J Neurooncol
September 2025
Department of Neurology, Xiangya Hospital, Central South University, No.87 Xiangya Road, Kaifu District, Changsha, 410008, Hunan Province, China.
Background And Objective: Differentiating central nervous system infections (CNSIs) from brain tumors (BTs) is difficult due to overlapping features and the limited individual indicators, and cerebrospinal fluid (CSF) cytology remains underutilized. To improve differential diagnosis, we developed a model based on 9 early, cost-effective cerebrospinal fluid parameters, including CSF cytology.
Methods: Patients diagnosed with CNSIs or BTs at Xiangya Hospital of Central South University between October 1st, 2017 and March 31st, 2024 were enrolled and divided into the training set and the test set.
Aim Search for subclinical manifestations of cardiotoxicity in cancer patients at high and very high risk of cardiotoxicity and evaluation of the effectiveness of drug primary prevention during the antitumor treatment. Material and methods The study included 150 cancer patients with a high and very high Mayo Clinic (USA) Cardiotoxicity Risk Score. The main group consisted of 84 patients at high and very high risk of cardiotoxicity who were prescribed cardioprotective therapy, including a fixed combination of the angiotensin-converting enzyme inhibitor (ACEI) perindopril and the beta-blocker bisoprolol with trimetazidine.
View Article and Find Full Text PDFCurr Med Imaging
September 2025
Department of Pharmacy, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Unlabelled: Leptomeningeal metastasis (LM) is a severe complication of solid malignancies, including lung adenocarcinoma, characterized by poor prognosis and diagnostic challenges. This study assesses whether curvilinear peri-brainstem hyperintense signals on MRI are a characteristic feature of LM in lung adenocarcinoma patients.
Methods: This retrospective study analyzed data from multiple centers, encompassing lung adenocarcinoma patients with peri-brainstem curvilinear hyperintense signals on MRI between January 2016 and March 2022.
Front Immunol
September 2025
Precision Pharmacy and Drug Development Center, Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Gliomas are the most common primary malignant tumors of the central nervous system (CNS), and despite progress in molecular diagnostics and targeted therapies, their prognosis remains poor. In recent years, immunotherapy has emerged as a promising treatment modality in cancer therapy. However, the inevitable immune evasion by tumor cells is a key barrier affecting therapeutic efficacy.
View Article and Find Full Text PDFFront Pediatr
August 2025
Department of Pediatrics, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, China.
Background And Objective: This study aims to analyze the clinical characteristics of anti-GABAR encephalitis in pediatric patients. Due to its rarity and diagnostic challenges in children, we compare clinical features between adult and pediatric cases.
Materials And Methods: Using the key words "anti-GABAR encephalitis, children, autoimmune encephalitis, limbic encephalitis", we conduct a comprehensive literature review of all studies related to anti-GABAR encephalitis published from January 2010 to January 2024.