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Phylogenetic studies have traditionally placed the simple Xenoacoelomorph worms as the sister group of all other animals with bilateral body symmetry. A new study shows that misidentification of orthologous genes might have been the source of at least some support for this placement.
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http://dx.doi.org/10.1016/j.cub.2022.11.019 | DOI Listing |
Proc Natl Acad Sci U S A
September 2025
Florida Museum of Natural History, University of Florida, Gainesville, FL 32611.
The origin and phylogenetic distribution of symbiotic associations between nodulating angiosperms and nitrogen-fixing bacteria have long intrigued biologists. Recent comparative evolutionary analyses have yielded alternative hypotheses: a multistep pathway of independent gains and losses of root nodule symbiosis vs. a single gain followed by numerous losses.
View Article and Find Full Text PDFBrief Bioinform
September 2025
Beijing Institute of Mathematical Sciences and Applications (BIMSA), Beijing 101408, P. R. China.
With the rapid development of genomic sequencing technologies, there is an increasing demand for efficient and accurate sequence analysis methods. However, existing methods face challenges in handling long, variable-length sequences and large-scale datasets. To address these issues, we propose a novel encoding method-Energy Entropy Vector (EEV).
View Article and Find Full Text PDFBMC Bioinformatics
September 2025
Genome Informatics, Faculty of Technology and Center for Biotechnology, Bielefeld University, 33615, Bielefeld, Germany.
Background: The increasing amount of available genome sequence data enables large-scale comparative studies. A common task is the inference of phylogenies- a challenging task if close reference sequences are not available, genome sequences are incompletely assembled, or the high number of genomes precludes multiple sequence alignment in reasonable time. SANS is an alignment-free, whole-genome based approach for phylogeny estimation.
View Article and Find Full Text PDFParasites Hosts Dis
August 2025
Public Health Genomics Lab, Faculty of Public Health, Universitas Diponegoro, Semarang 50275, Indonesia.
Baseline genetic characterization of malaria vector populations provides critical data for evidence-based surveillance in persistent transmission foci. This pilot study generated preliminary genetic baseline data for Anopheles populations in the Menoreh Hills border region between Central Java and Yogyakarta provinces, Indonesia, addressing a key geographic gap in regional vector research. Adult female mosquitoes were collected from 3 houses with reported malaria cases in Ngadirejo Village using standardized entomological methods, including human landing, animal landing, and resting collections.
View Article and Find Full Text PDFGenes (Basel)
July 2025
College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.
: is widely utilized in the fermentation industry and offers potential health benefits. However, large-scale comparative genomic analyses aimed at exploring its metabolic functions and conducting safety assessments are still lacking. : In this study, we performed a comparative genomic analysis of 324 strains sourced from various origins and geographical locations.
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