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Fairly accurate. Photometric transcutaneous bilirubin (TcB) testing may overestimate total serum bilirubin (TSB) in neonates with darker skin tones by a mean of 0.68 to > 2 mg/dL (strength of recommendation [SOR]: C, diagnostic cohort studies with differing reference standards).Overall, TcB meters retain accept able accuracy in infants of all skin tones across a range of bilirubin levels, despite being more likely to underestimate lighter skin tones and overestimate darker ones (SOR: C, diagnostic cohort studies with differing reference standards). It is unclear if the higher readings prompt an increase in blood draws or otherwise alter care.
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http://dx.doi.org/10.12788/jfp.0502 | DOI Listing |
J Vis Exp
August 2025
The Ragon Institute of Mass General, MIT, and Harvard Main Street;
Ultraviolet B (UVB) radiation (280-320 nm) has been recognized as a carcinogen since 1928, leading to sun exposure minimization. However, epidemiological studies suggest that sun exposure correlates with increased life expectancy and reduced incidence of cardiovascular diseases and certain cancers such as colon and endometrial cancer. UVB exposure also influences liver metabolism, protects against hepatocellular lipotoxicity, and affects metabolic health.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
September 2025
Pediatric Endocrinology Department, Obesity, Endocrine and Metabolism Center, King Fahd Medical City, Riyadh, Saudi Arabia.
McCune-Albright syndrome (MAS) is a rare genetic disorder characterized by a triad of café-au-lait spots, fibrous dysplasia, and hyperfunctioning endocrinopathies, resulting from a mosaic mutation in the guanine nucleotide-binding protein (GNAS) gene. This case report presents the long-term follow-up of an eight-year-old girl diagnosed with MAS, who first presented at 22 months of age with skin pigmentation, hyperthyroidism, and precocious puberty, later developing additional features such as fibrous dysplasia and growth hormone excess. This complex presentation of MAS-featuring more than two hyperfunctioning endocrinopathies along with fibrous dysplasia-has rarely been described in the literature.
View Article and Find Full Text PDFJ Cosmet Dermatol
September 2025
Department of Dermatology, Nantong Third People's Hospital, Affiliated Nantong Hospital 3 of Nantong University, Nantong, China.
Purpose: To evaluate the efficacy and underlying mechanism of advanced optimal pulse technology intense pulsed light (AOPT) in low-energy triple-pulse long-width mode (AOPT-LTL) for melasma treatment.
Methods: An in vivo guinea pig model of melasma was established through progesterone injection and ultraviolet B radiation. Three sessions of AOPT-LTL treatment were performed weekly.
Poult Sci
September 2025
Laboratory of Chemical Research and Instrumental Analysis, Faculty of Animal Breeding and Biology, Bydgoszcz University of Science and Technology, Mazowiecka 28, 85-084, Bydgoszcz, Poland.
The objective of this study was to evaluate the effect of dietary inclusion of different carrot forms on production results, carcass traits, meat quality, fatty acid (FA) composition, vitamin content, and feed costs in Cherry Valley broiler ducks. A total of 240 one-day-old males (initial body weight of 55.2 g) were allocated to 4 treatments (n = 60; 6 replicates of 10 birds): control (CD; 100 % commercial diet), CFL (CD + 2 % carrot flakes), RAWC (80 % CD + 20 % raw carrot), and CPOW (CD + 2 % carrot powder).
View Article and Find Full Text PDFMol Genet Genomics
September 2025
Institute of Genetics, Vetsuisse Faculty, University of Bern, 3012, Bern, Switzerland.
The aim of this study was to investigate three unrelated Simmental calves with atypical white coat color, identify potential genetic causes using a trio-based whole-genome sequencing approach, and assess the prevalence of the identified variants in the breed. Several inherited alleles affecting coat color, ranging from fawn to red spotted and white-headed, have been described in Simmental cattle originating from Switzerland. However, no genetic variant has yet been associated with an almost completely white coat in this breed.
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