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Background: This study examined the relationship between alcohol consumption and total testosterone deficiency based on facial flushing among Korean men.
Methods: A total of 314 men were included in this study and divided into non-drinkers (n=78) and drinkers (n=236). Drinkers were also divided into flushers (n=96) and non-flushers (n=140). Flushers and non-flushers were separated into two groups based on the amount of alcohol consumed: moderate drinkers (≤8 standard drinks per week) and heavy drinkers (>8 standard drinks per week). Total testosterone <3.5 ng/mL was defined as testosterone deficiency.
Results: The risk of testosterone deficiency was significantly higher in heavy drinkers who flushed than in nondrinkers (odds ratio, 4.37; 95% confidence interval, 1.20-15.88; P=0.025). However, no significant difference was observed in the risk of testosterone deficiency in non-flushers, regardless of the amount of alcohol consumed.
Conclusion: This study suggests that the risk of testosterone deficiency increases in heavy drinkers (>8 drinks per week) who flush compared to that in non-drinkers.
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http://dx.doi.org/10.4082/kjfm.21.0173 | DOI Listing |
JMIR Res Protoc
September 2025
Center for Alcohol & Addiction Studies, School of Public Health, Brown University, Providence, RI, United States.
Background: Digital media frequently contains positive portrayals of alcohol content, which has been shown to be associated with alcohol-related cognitions and behaviors. Because youth are heavy media consumers and have access to unsupervised, repeat viewing of media content on their personal mobile devices, it is critical to understand the frequency of encountering alcohol content in adolescents' daily lives and how adolescents engage with the content.
Objective: This paper outlines the study protocol for examining adolescents' exposure to alcohol-related content in digital media within their natural environments.
Alcohol
September 2025
Department of Psychology, Idaho State University, Pocatello, ID, USA.
Background: Prior longitudinal studies demonstrate that sleep disturbance is a risk factor for alcohol misuse. Experimental research also shows that alcohol intake negatively impacts sleep. The present study evaluated temporal bidirectional relationships between sleep and alcohol intake using intensive longitudinal methods.
View Article and Find Full Text PDFJ Neuroimmunol
September 2025
The University of Texas at Austin, College of Pharmacy, Division of Pharmacology & Toxicology, Austin, TX, 78712, United States of America. Electronic address:
Adolescents who consume alcohol show a high prevalence of binge drinking, which has been linked to brain damage and neuroimmune reactions that increase risk for developing an alcohol use disorder (AUD). Adolescent female drinking patterns have surpassed males, yet little is known about damaging effects of alcohol in females. Known sex differences in neuroimmune reactivity, specifically microglial reactivity, suggest that the female brain will differ from males.
View Article and Find Full Text PDFBMJ Open
September 2025
Psychologial Neuroscience Laboratoy (PNL), Psychology Research Center (CIPSI), School of Psychology, University of Minho, Braga, Portugal
Introduction: Adolescence and youth are periods of significant maturational changes, which seem to involve greater susceptibility to disruptive events in the brain, such as binge drinking (BD). This pattern-characterised by repeated episodes of alcohol intoxication-is of particular concern, as it has been associated with significant alterations in the developing brain. Recent evidence indicates that alcohol may also induce changes in gut microbiota composition and that such disturbances can lead to impairments in both brain function and behaviour.
View Article and Find Full Text PDFJ Trace Elem Med Biol
August 2025
Department of Neurology, Barrow Neurological Institute, Phoenix, AZ, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Parktown, South Africa.
Background: Excessive exposure to manganese (Mn) causes parkinsonism. Occupational Mn exposure is associated with increased T1-weighted globus pallidus signal on magnetic resonance imaging (MRI) secondary to in-vivo Mn deposition.
Methods: The present study evaluated the T1-weighted pallidal index (PI) as an in-vivo marker of Mn exposure and neurotoxicity in chronic environmental Mn exposure.