Antimicrobial activity, chemical composition and mechanism of action of Chinese chive ( Rottler) extracts.

Front Microbiol

Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, Sichuan, China.

Published: November 2022


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Article Abstract

Chinese chive ( Rottler) is a popular food from species in East and Southeast Asia. Most species possess characteristic aromas and have antimicrobial activity. In this study, the antimicrobial activities of root, leaf, and scape extracts of Chinese chive at different pH levels (3.0, 5.0, 7.0, 9.0, and 10.7) were compared. The most pronounced activity was produced by the scape extract, and the greatest activity was obtained at pH 5.0. HPLC and GC-MS analysis showed that the major active ingredient was 2-amino-5-methylbenzoic acid. The mechanism of action of Chinese chive scape extracts may involve the depression or disruption of cell membrane integrity, according to our results of the leakage of electrolytes and protein, as well as scanning electron microscopy and transmission electron microscopy observations.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664698PMC
http://dx.doi.org/10.3389/fmicb.2022.1028627DOI Listing

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