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Article Abstract
• Deletion of residues 156–157 warps the neighboring beta-sheet and leads NTD and RBD to shift. • T859N stabilizes the packing of the 630 loop motif to make RBD standing transition more difficult. • The overall structures of the closed state S complex from different variants resemble each other. • Mutations in FPPR may affect the overall structure of the trimeric spike protein.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642027 | PMC |
| http://dx.doi.org/10.1016/j.virs.2022.11.003 | DOI Listing |
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