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http://dx.doi.org/10.1080/03007995.2022.2139970 | DOI Listing |
BMC Nurs
September 2025
Nursing Administration, Faculty of Nursing, Mansoura University, Mansoura, Egypt.
Borderline Personal Disord Emot Dysregul
September 2025
German Center for Mental Health (DZPG), partner site Munich, Munich, Germany.
Background: Emotion dysregulation is a central feature in trauma-associated disorders such as posttraumatic stress disorder (PTSD) and borderline personality disorder (BPD). However, it remains unclear whether emotion dysregulation is a transdiagnostic phenomenon closely linked to childhood trauma, or if disorder-specific alterations in emotion processing exist. Following a multimethodological approach, we aimed to assess and compare the reactivity to and regulation of emotions between patients with BPD and PTSD, as well as healthy controls, and identify associations with childhood trauma.
View Article and Find Full Text PDFBMC Med Educ
September 2025
Department of Prosthodontics, University of Würzburg, Pleicherwall 2, 97070, Würzburg, Germany.
Background: Bridge preparation skills are a vital component of dental education and require specific techniques. This study aimed to develop and evaluate 3D printed teeth for use in defect-oriented bridge preparation and pre-prosthetic exercises in dental training, addressing the limited customization and lack of integrated workflows found in commercial typodont teeth. The null hypothesis stated that 3D printed teeth offered no advantage over established typodont training methods for bridge preparation.
View Article and Find Full Text PDFBMC Nurs
September 2025
Nursing Administration Department, Faculty of Nursing, Tanta University, Tanta, Egypt.
Background: Nursing interns frequently encounter role ambiguity due to a mismatch between their expectations of the professional nursing role and the actual responsibilities they face in clinical settings. While clinical rotations during the internship year are intended to enhance clinical confidence and competence, such ambiguity can undermine these goals.
Objective: To examine the relationship between internship clinical rotation and role ambiguity among nursing interns.
J Biomed Sci
September 2025
Division of Gastroenterology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Oncometabolites are aberrant metabolic byproducts that arise from mutations in enzymes of the tricarboxylic acid (TCA) cycle or related metabolic pathways and play central roles in tumor progression and immune evasion. Among these, 2-hydroxyglutarate (2-HG), succinate, and fumarate are the most well-characterized, acting as competitive inhibitors of α-ketoglutarate-dependent dioxygenases to alter DNA and histone methylation, cellular differentiation, and hypoxia signaling. More recently, itaconate, an immunometabolite predominantly produced by activated macrophages, has been recognized for its dual roles in modulating inflammation and tumor immunity.
View Article and Find Full Text PDF