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Purpose: To investigate the MRI features associated with neural foraminal stenosis (NFS) in patients older than 60 years with lumbar (L) radiculopathy.
Materials And Methods: This study included 133 retrospectively selected patients older than 60 years with lumbar radiculopathy who had undergone a lumbar spine MRI (from January 2018 to April 2018). For L4/L5 and L5/sacral (S)1 levels, NFS was reviewed blindly by two radiologists. Spondylolisthesis, retrolisthesis, disc height loss, disc bulging/herniation/central canal stenosis, ligamentum flavum thickening, and facet hypertrophy were evaluated separately for the NFS and non-NFS groups, and they were compared using univariate and multivariate analyses.
Results: The univariate analysis revealed that disc height loss ( = 0.006) was associated with NFS for L4/L5. For L5/S1, both spondylolisthesis ( = 0.005) and facet hypertrophy ( = 0.006) were associated with NFS. The multivariate logistic analysis revealed that disc height loss was associated with NFS for L4/L5 [odds ratio (OR) = 4.272; 95% confidence interval (CI) 1.736-10.514]. For L5/S1, spondylolisthesis (OR = 3.696; 95% CI 1.297-10.530) and facet hypertrophy (OR = 6.468; 95% CI 1.283-32.617) were associated with NFS.
Conclusion: Disc height loss was associated with NFS for L4/L5 and spondylJophy were associated with NFS for L5/S1.
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http://dx.doi.org/10.3348/jksr.2020.0095 | DOI Listing |
J Interpers Violence
September 2025
Texas A&M-San Antonio, USA.
Risk assessments performed in the context of community supervision provide a unique opportunity to identify characteristics associated with high-risk domestic violence (DV) offenders. To date, however, few studies have used such data to explore the factors that differentiate offenders who have engaged in nonfatal strangulation (NFS) to other less severe forms of DV. Using data from the Wisconsin Risk Need assessment, the present study compares risk and need factors for offenders sentenced to probation for an offense involving NFS to a misdemeanor DV offense ( = 909).
View Article and Find Full Text PDFAm J Clin Oncol
September 2025
Department of Head and Neck-Endocrine Oncology.
Objectives: We report on the biomarker analyses focusing on neutrophil-to-lymphocyte ratios (NLR) in patients with recurrent and/or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) treated with combined cetuximab and nivolumab.
Methods: Data were obtained from a phase II trial (NCT03370276). Peripheral blood NLR was obtained at baseline (B-NLR) and on-treatment (OT-NLR; 1 mo from treatment initiation).
Int J Geriatr Psychiatry
September 2025
The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Objectives: Lack of formal schooling remains prevalent among older adults in China, particularly in rural areas. This study investigates the cognitive function trajectory and influencing factors in older adults without formal schooling from the Chinese Longitudinal Healthy Longevity Survey (CLHLS).
Methods: The study included 2159 individuals without formal schooling (NFS) and 2234 individuals with formal schooling (FS), all cognitively healthy and aged over 60 at the first observation from the 2008 - 2018 CLHLS cohort.
Anticancer Res
September 2025
Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Background/aim: Oral squamous cell carcinoma (OSCC) is a common malignancy with a poor prognosis, partly due to interactions within the tumor microenvironment. Cancer-associated fibroblasts (CAFs), key stromal components, promote tumor progression by enhancing cancer cell migration, angiogenesis, and extracellular matrix remodeling. Transforming growth factor-beta (TGF-β) is known to induce CAF differentiation from normal fibroblasts (NFs), but its functional contribution in OSCC remains to be fully elucidated.
View Article and Find Full Text PDFMar Mamm Sci
May 2025
University of Washington, Cooperative Institute for Climate, Ocean, and Ecosystem Studies, Seattle, WA, USA.
In August 2024, a northern fur seal mortality event was observed on St. Paul Island, AK in the southeast (SE) Bering Sea. Ten seals in good body condition were found dead along with large accumulations of dead fish on Benson Beach located on St.
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