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Background: Uterus transplantation is the only treatment for absolute uterine factor infertility. Complex vascular anatomy, long operation time, and intraoperative injuries are the main factors that limit progress in uterus transplantation. Moreover, robot-assisted uterus transplantation is not popular at present due to technical difficulties, with only a few countries reporting success.
Methods: In this paper, we present the key technical points of robot-assisted uterine transplantation by analyzing and summarizing our surgical experience and other successful cases of robot-assisted uterine transplantation. This study provides an evidence-based reference for clinicians planning robot-assisted uterine transplantation procedures.
Conclusion: Minimally invasive technologies can shorten the operation time, reduce injuries, and contribute to analyzing the anatomy of complex blood vessels. Therefore, robot-assisted uterine transplantation is an important direction for the future of uterine transplantation, and the findings and procedures reported herein contribute to the standardization and promotion of robot-assisted uterine transplantation operations.
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http://dx.doi.org/10.1007/s00404-022-06791-y | DOI Listing |
Arch Med Res
September 2025
Instituto Mexicano de Infertilidad, Zapopan, Jalisco, Mexico. Electronic address:
This study examines uterine transplantation (UTx) in 2024. It focuses on various aspects, such as animal models, clinical outcomes, surgical procedures, patient perspectives, and ethical and legal considerations. The study particularly considers the context of Mexico.
View Article and Find Full Text PDFTissue Eng Regen Med
September 2025
Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Korea.
Background: Endometrial damage is a critical factor contributing to infertility, particularly in women with refractory thin endometrium or intrauterine adhesions. Therefore, developing innovative therapeutic strategies for endometrial regeneration is essential. This study evaluates the regenerative potential of endometrial stromal cell (EMSC) injection and EMSC-loaded patch application in a mouse model with ethanol-induced endometrial damage.
View Article and Find Full Text PDFFront Oncol
August 2025
Division of Hematology, Department of Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Extramedullary relapse of acute lymphoblastic leukemia (ALL) is usually associated with poor prognosis. Chimeric antigen receptor T cell (CAR-T cell) therapy followed by allogeneic hematopoietic stem cell transplantation is beneficial for relapsed/refractory (r/r) B cell acute lymphoblastic leukemia (B-ALL). Here, we report a B-ALL patient with extramedullary relapse involving several organs, including multiple lymph nodes and the breast, kidney, uterus and pancreas.
View Article and Find Full Text PDFGeburtshilfe Frauenheilkd
September 2025
Institute for Molecular and Cellular Anatomy, University of Regensburg, Regensburg, Germany.
Aim: Endometriosis is a gynecological disorder characterized by endometrial-like tissue outside the uterus. This study evaluates the vascularization and proliferation of human endometriosis and endometrium tissues engrafted onto the chorioallantoic membrane of chicken embryos using immunohistochemistry and laser speckle contrast analysis imaging. For the assessment of clinical relevance, a comparison between laboratory and clinical data was performed.
View Article and Find Full Text PDFStem Cell Rev Rep
September 2025
college of nursing, National University of Science and Technology, Dhi Qar, Iraq.
Regenerative engineering (RE) is the convergence of advanced stem cell science, material science, physics, clinical translation, and developmental biology to regenerate organ and complex tissue systems. It is a development of tissue engineering, which was first advanced as a method of restoration and repair of human tissue. In recent years, advances in regenerative techniques have shown promise in treating various clinical problems using existing advanced technology to harness the body's therapeutic and regenerative abilities.
View Article and Find Full Text PDF