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Background: The transversus abdominus plane (TAP) block reduces postoperative donor site pain in patients undergoing autologous breast reconstruction with an abdominally based flap. This study aimed to determine the effect of TAP blocks on rates of conversion to chronic opioid use.
Methods: The Clinformatics Data Mart was queried from 2003 to 2019, extracting adult encounters for abdominally based free and pedicled flaps based on common procedural terminology (CPT) codes. Patients were excluded if they had filled a narcotic prescription 1 year to 30 days prior to surgery. The exposure variable-TAP block-was identified by CPT codes. Outcomes were evaluated using morphine milligram equivalents (MME) from prescriptions filled between 30 days prior to and 30 days after surgery. Chronic opioid use (COU) was defined as receiving 4 unique prescriptions or a 60-day supply between 30 and 180 days after surgery.
Results: Of the 4091 patients, (mean age 51.2 ± 9.0 years), 181 (4.4%) had a TAP block placed. Perioperative MMEs/day, postoperative COU, and length of stay did not differ in patients who received a TAP block (p = 0.142; p = 0.271). Significant predictors of risk of conversion to COU included younger age, pedicled abdominal flap, Elixhauser comorbidity index score > 3, filling a psychiatric medication prescription, and filling a benzodiazepine prescription.
Conclusions: In patients undergoing autologous breast reconstruction with abdominally based flap reconstruction, TAP blocks do not decrease perioperative MME/day, conversion to chronic opioid use, or length of stay. These data suggest that intraoperative TAP block placement may be a low-yield opioid-reduction strategy.Level of evidence: Level III, risk/prognostic study.
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http://dx.doi.org/10.1007/s00238-022-01996-5 | DOI Listing |
Vet Res Commun
September 2025
Centro de Investigación en Alimentación y Desarrollo, A.C. Subsede Mazatlán en Acuicultura y Manejo Ambiental, Av. Sábalo-Cerritos S/N, Mazatlán 82112, Sinaloa, México.
Histological analysis is a method commonly used in medical clinics to evaluate biological tissues and their abnormalities. However, this method is based on tissue collected from the necropsy of the animal, where modifications in the tissue associated with autolysis can occur after death. This study analyses the post-mortem histomorphological changes in white shrimp (Penaeus vannamei) after euthanasia by clove oil anaesthesia induction and pithing as a secondary killing method.
View Article and Find Full Text PDFAbdom Radiol (NY)
September 2025
Department of Gastroenterology department, Bishan Hospital of Chongqing Medical University, Chongqing, China.
Objective: This study aimed to create and validate a nomogram to predict early recurrence (ER) in Colorectal cancer (CRC) patients by combining CT-derived abdominal fat parameters with clinical and pathological characteristics.
Methods: We conducted a retrospective analysis of 206 CRC patients, dividing them into training (n = 146) and validation (n = 60) cohorts. We quantified abdominal fat parameters, including subcutaneous adipose tissue index (SATI) and visceral adipose tissue index (VATI), using semi-automatic software on CT images at the level of the third lumbar vertebra (L3).
Abdom Radiol (NY)
September 2025
Research Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK.
Objectives: The escalating global incidence of obesity, cardiometabolic disease and sarcopenia necessitates reliable body composition measurement tools. MRI-based assessment is the gold standard, with utility in both clinical and drug trial settings. This study aims to validate a new automated volumetric MRI method by comparing with manual ground truth, prior volumetric measurements, and against a new method for semi-automated single-slice area measurements.
View Article and Find Full Text PDFFolia Parasitol (Praha)
September 2025
Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, Ceske Budejovice, Czech Republic.
Taenia crassiceps (Zeder, 1800), a zoonotic cestode with a wide geographical distribution, utilises canids as definitive hosts and small rodents as intermediate hosts. However, accidental infections in non-human primates, particularly in captive lemurs, have been increasingly documented. In this case report, we describe the first documented case of cysticercosis caused by the larval stage of T.
View Article and Find Full Text PDFTurkiye Parazitol Derg
September 2025
COMSATS University Islamabad (CUI) Faculty of Health Sciences, Department of Biosciences, Islamabad, Pakistan.
Objective: Present study aimed to determine the demographic, epidemiological and pathological features of human cystic echinococcosis (CE) cases using patients' hospital based clinical history from 2012-2023.
Methods: The current retrospective study was conducted from June-December and aimed to investigate the incidence of human CE in Pakistan. A total of 74 surgically confirmed patients' data was retrieved from the hospital records.