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Article Abstract
The Red Sea soft coral ethyl acetate extract has afforded one new cembranoid; sarcacutumolid A (), along with six known metabolites have been isolated from for the first time (). Chemical structures were elucidated by employing several spectroscopic analyses. The cytotoxic potential of the isolated compounds was assessed against four human cancer cell lines; hepatocellular (HepG2), cervical (HeLa), breast (MCF-7) and colorectal cancer (Colo-205). Sarcacutumolid A () and gorgosterol () inhibited colorectal cancer cell proliferation in a concentration-dependent manner with IC values of 35.5 and 44.0 μM, respectively.
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| http://dx.doi.org/10.1080/14786419.2022.2130915 | DOI Listing |
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