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http://dx.doi.org/10.1007/s00299-022-02925-3 | DOI Listing |
J Chem Phys
September 2025
Department of Inorganic Chemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská dolina, Ilkovičova 6, SK-84215 Bratislava, Slovakia.
An explicitly correlated extension of a pair-function based perturbation theory is presented. The reference is obtained as the antisymmetrized product of strongly orthogonal geminals, termed Strictly Localized Geminals (SLG), which can capture static correlation at mean-field cost. Geminals entering SLG are spin unrestricted, in general, and are expanded in the one-electron basis of the natural orbitals of the unrestricted Hartree-Fock wavefunction.
View Article and Find Full Text PDFRetin Cases Brief Rep
October 2024
Eye Clinic, Humanitas-Gradenigo Hospital, Torino, Italy.
Purpose: To study the efficacy and safety of pro re nata regimen of brolucizumab, without loading dose, in treatment-naive patients with neovascular age-related macular degeneration (nAMD).
Case Series: Retrospective, observational study. We included all consecutive patients diagnosed with treatment- naïve nAMD undergoing Brolucizumab in Humanitas eye clinic, Turin, Italy between April 2022 and May 2023.
Clin Kidney J
September 2025
Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Rome, Italy.
Genome editing technologies, particularly clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9, have transformed biomedical research by enabling precise genetic modifications. Due to its efficiency, cost-effectiveness and versatility, CRISPR has been widely applied across various stages of research, from fundamental biological investigations in preclinical models to potential therapeutic interventions. In nephrology, CRISPR represents a groundbreaking tool for elucidating the molecular mechanisms underlying kidney diseases and developing innovative therapeutic approaches.
View Article and Find Full Text PDFAlpha Psychiatry
August 2025
Information Sciences and Technology, George Mason University, Fairfax, VA 22030, USA.
Background: Herein, we report on the initial development, progress, and future plans for an autonomous artificial intelligence (AI) system designed to manage major depressive disorder (MDD). The system is a web-based, patient-facing conversational AI that collects medical history, provides presumed diagnosis, recommends treatment, and coordinates care for patients with MDD.
Methods: The system includes seven components, five of which are complete and two are in development.
Vet Dermatol
September 2025
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA.
Background: The antibacterial efficacy of chlorhexidine shampoo is directly affected by formulation and bathing factors.
Hypothesis/objective: To evaluate the in vitro antibacterial efficacy of chlorhexidine-containing shampoos at various dilutions and to compare their lathering ability.
Animals: No animals were utilised in this study.