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Event-related potentials (ERP) are brain-evoked potentials that reflect the neural activity of the brain. However, it is difficult to isolate the ERP components of our interest because single-trial EEG is disturbed by other signals, and the average ERP analysis in turn loses single-trial information. In this paper, we used electrophysiological source imaging (ESI) to analyze the N170 component of single-trial EEG triggered by face stimulation. The results show that ESI is feasible for the analysis of N170 and that there are left-right differences in the area of the fusiform gyrus associated with face stimulation in the brain. Clinical Relevance- Analysis of the N170 of single-trial EEG by ESI may help in the diagnosis of patients with prosopagnosia and may also help physicians clinically in determining whether the fusiform gyrus region is damaged.
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http://dx.doi.org/10.1109/EMBC48229.2022.9871791 | DOI Listing |
Sci Data
September 2025
State Laboratory of Cognitive Science and Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, 100101, China.
Understanding the neural mechanisms of pain is key to the development of novel pain diagnostic and treatment strategies. Here, we present a large-scale, comprehensive electroencephalogram (EEG) dataset of laser-evoked potentials (LEPs) from 678 healthy participants. This dataset comprises high-density EEG recordings and single-trial self-reported pain ratings in response to nociceptive laser stimuli of varying intensities (from 2.
View Article and Find Full Text PDFIEEE Trans Neural Syst Rehabil Eng
September 2025
The practical deployment of P300-based brain-computer interfaces (BCIs) has long been hindered by the need for user-specific calibration and multiple stimulus repetitions. In this study, we build and validate a plug-and-play, zero-training P300 BCI system that operates in a single-trial setting using a pre-trained xDAWN spatial filter and a deep convolutional neural network. Without any subject-specific adaptation, participants could control an IoT device via the BCI system in real time, with decoding accuracy reaching 85.
View Article and Find Full Text PDFJ Neural Eng
September 2025
National Center for Adaptive Neurotechnology, Stratton Veterans Affairs Medical Center, Albany, NY 12208, United States of America.
Reliable extraction of single-trial somatosensory evoked potentials (SEPs) is essential for developing brain-computer interface (BCI) applications to support rehabilitation after brain injury. For real-time feedback, these responses must be extracted prospectively on every trial, with minimal post-processing and artifact correction. However, noninvasive SEPs elicited by electrical stimulation at recommended parameter settings (0.
View Article and Find Full Text PDFImaging Neurosci (Camb)
May 2025
Psychology, University of Dundee, Dundee, United Kingdom.
Research on brain-behaviour relationships often makes the implicit assumption that these derive from a co-variation of stochastic fluctuations in brain activity and performance across trials of an experiment. However, challenging this assumption, oscillatory brain activity, as well as indicators of performance, such as response speed, can show systematic trends with time on task. Here, we tested whether time-on-task trends explain a range of relationships between oscillatory brain activity and response speed, accuracy as well as decision confidence.
View Article and Find Full Text PDFImaging Neurosci (Camb)
February 2025
Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.
The auditory mismatch negativity (MMN) has been widely used to investigate deficits in early auditory information processing, particularly in psychosis. Predictive coding theories suggest that impairments in sensory learning may arise from disturbances in hierarchical message passing, likely due to aberrant precision-weighting of prediction errors (PEs). This study employed a modified auditory oddball paradigm with varying phases of stability and volatility to disentangle the impact of hierarchical PEs on auditory MMN generation in 43 healthy controls (HCs).
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