Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Maternal nutrition represents a critical risk factor for adverse health outcomes in both mother and offspring. We aimed to investigate associations between maternal nutritional habits, biomarker status, and pregnancy outcome among Italian healthy normal-weight pregnancies. Multicenter prospective cohort study recruiting Italian healthy normal-weight women with singleton spontaneous pregnancies at 20 ± 2 weeks (T1) in Milan and Naples. All patients underwent nutritional evaluations by our collecting a 7-day weighed dietary record at 25 ± 1 weeks (T2) and a Food Frequency Questionnaire at 29 ± 2 weeks (T3). Maternal venous blood samples were collected at T3 to assess nutritional, inflammatory and oxidative biomarker concentrations (RBCs folate, vitamin D, hepcidin, total antioxidant capacity). Pregnancy outcomes were collected at delivery (T4). General linear models adjusted for confounding factors were estimated to investigate associations between maternal dietary pattern adherence, nutrient intakes, biomarker concentrations and delivery outcomes. 219 healthy normal-weight pregnant women were enrolled. Vitamin D and RBCs folate concentrations, as well as micronutrient intakes, were consistently below the recommended range. In a multi-adjusted model, maternal adherence to the most prevalent 'high meat, animal fats, grains' dietary pattern was positively associated with hepcidin concentrations and negatively associated with gestational age at delivery in pregnancies carrying female fetuses. Hepcidin plasma levels were further negatively associated to placental weight, whereas vitamin D concentrations were positively associated to neonatal weight. A high adherence to an unbalanced 'high meat, animal fats, grains' pattern was detected among Italian normal-weight low-risk pregnancies, further associated with maternal pro-inflammatory status and gestational age at delivery. This evidence underlines the need for a dedicated nutritional counseling even among low-risk pregnancies.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460547 | PMC |
| http://dx.doi.org/10.3390/nu14173631 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evolution of osteitis condensans ilii-like sclerosis in first-time mothers by serial sacroiliac joint MRI during pregnancy and in the postpartum period.
Ann Rheum Dis
September 2025
Department of Radiology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Objectives: This study aims to evaluate the evolution of subchondral sacroiliac joint (SIJ) sclerosis from pregnancy to 12 months postpartum, and to explore preceding and concomitant magnetic resonance imaging (MRI) features, potentially indicating osteitis condensans ilii (OCI).
Methods: One hundred three first-time mothers were recruited for serial SIJ MRIs. MRI scans were performed at pregnancy weeks 20 and 32, and at 3, 6, and 12 months postpartum.
Meta-analysis of the association between prenatal antibiotic exposure and risk of childhood attention-deficit/hyperactivity disorder.
J Affect Disord
September 2025
Department of emergency, West China Second University Hospital, Sichuan University, Chengdu, 610041, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, 610041, China; Department of Emergency, Chengdu Hi-Tech Zone Ho
Background: Studies examining the association between maternal antibiotic use during pregnancy and the risk of childhood attention-deficit/hyperactivity disorder (ADHD) have yielded inconsistent results. This meta-analysis synthesizes available evidence to establish a more comprehensive understanding of this association.
Methods: Observational studies published through October 2, 2024, were systematically searched from Cochrane Library, EMBASE, Web of Science, and PubMed databases.
Do purpose in life and self-directedness mediate the effects of child abuse on anxiety and depression symptoms 18 years later?
J Affect Disord
September 2025
National University of Singapore (NUS), Department of Psychology, Singapore. Electronic address:
Background: Childhood maltreatment is a transdiagnostic risk factor that is robustly associated with the development of anxiety and depressive disorder symptoms in adulthood. This study thus aimed to investigate potential mediators between early childhood abuse and adult psychopathology severity using data from an 18-year longitudinal study among community-dwelling adults in the U.S.
View Article and Find Full Text PDFExploring why adolescents of disadvantaged family socio-economic status were more depressed than others: Serial mediations via personal psychological resources, loneliness, and school refusal functions.
J Affect Disord
September 2025
School of Mental Health, Wenzhou Medical University, Wenzhou, China; The Affiliated Wenzhou Kangning Hospital, Wenzhou Medical University, Wenzhou, China; Center for Health Behaviours Research, Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, Chin
Background: Disadvantageous family socio-economic status (DFSES) is a potential source of disparity in adolescent mental health. This study investigated the association between DFSES and probable depression and its mediation mechanisms via personal psychological resources (hope and resilience), loneliness, and school refusal functions.
Methods: A school-based anonymous survey was conducted among 8285 middle school students in China from February to March 2022; the response/eligible rate was 98.
Metataxonomic and bacterial culture studies of breast milk microbiota in mothers of premature infants: factors influencing its bacterial composition and diversity.
J Nutr
September 2025
Université Paris-Saclay, CEA, Centre National de Recherche en Génomique Humaine (CNRGH), 91057 Evry, France. Electronic address:
Background: Breast milk represents the optimal feeding strategy for newborns, supporting not only nutrition but also the establishment of a unique microbiota. The bacterial composition and diversity of this microbiota are shaped by various maternal and infant-related factors.
Objectives: This single-center prospective study aimed to examine the breast milk microbiota and determine the maternal and infant-related factors influencing its composition and diversity over the time.