A flexible framework for visualizing and exploring patient misdiagnosis over time.

J Biomed Inform

University of Utah School of Medicine Division of Epidemiology, 295 Chipeta Way, Salt Lake City, 84132, UT, USA; VA Salt Lake City Health Care System, 500 Foothill Dr, Salt Lake City, 84148, UT, USA. Electronic address:

Published: October 2022


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Diagnosis is a complex and ambiguous process and yet, it is the critical hinge point for all subsequent clinical reasoning and decision-making. Tracking the quality of the patient diagnostic process has the potential to provide valuable insights in improving the diagnostic accuracy and to reduce downstream errors but needs to be informative, timely, and efficient at scale. However, due to the rate at which healthcare data are captured on a daily basis, manually reviewing the diagnostic history of each patient would be a severely taxing process without efficient data reduction and representation. Application of data visualization and visual analytics to healthcare data is one promising approach for addressing these challenges. This paper presents a novel flexible visualization and analysis framework for exploring the patient diagnostic process over time (i.e., patient diagnosis paths). Our framework allows users to select a specific set of patients, events and/or conditions, filter data based on different attributes, and view further details on the selected patient cohort while providing an interactive view of the resulting patient diagnosis paths. A practical demonstration of our system is presented with a case study exploring infection-based patient diagnosis paths.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbi.2022.104178DOI Listing

Publication Analysis

Top Keywords

patient diagnosis
12
diagnosis paths
12
patient
8
exploring patient
8
patient diagnostic
8
diagnostic process
8
healthcare data
8
data
5
flexible framework
4
framework visualizing
4

Similar Publications

Persisting Lyme Disease in the Pediatric Population.

Clin Pediatr (Phila)

September 2025

Department of Medicine (Infectious Disease), University of Connecticut Health Center, Boston University Medical Center, Falmouth Hospital, Falmouth, MA, USA.

A total of 101 patients with a clinical picture of persisting Lyme disease seen at the University of Connecticut Health Center and Boston Medical Center were recruited for the study to determine whether persistent infection is the likely cause. Brain SPECT imaging and responses to antibiotic treatments were recorded. Patients had more than 5 symptoms lasting more than 6 months.

View Article and Find Full Text PDF

Objectives: Acute pyelonephritis (APN) is a common diagnosis among patients presenting to the Emergency Department (ED). It is treated by empiric antibiotics within the ED. With a rise in antimicrobial resistance globally, it is unknown whether patients are being managed with empiric antibiotics that are appropriate for the causative organisms of APN.

View Article and Find Full Text PDF

Description of a patient with multiple sclerosis (MS) who underwent immunotherapy with ocrelizumab and suffered a severe course of tick-borne encephalitis (TBE): A 33-year-old man presented with acute cerebellitis with tonsillar herniation. The initial suspected diagnosis of TBE was confirmed after a significant diagnostic delay, likely caused by negative serological testing due to B-cell depletion from ocrelizumab treatment for underlying MS. TBE diagnosis was made using polymerase chain reaction (PCR) and oligo-hybrid capture metagenomic next-generation sequencing (mNGS) of cerebral spinal fluid and brain biopsy samples which yielded a near-full length TBE Virus (TBEV) genome.

View Article and Find Full Text PDF

Objective: This study investigated the relationship of maternal serum uric acid, cystatin C (CysC), and coagulation indices [international normalized ratio (INR) and fibrinogen (FIB)] during pregnancy with clinical features and prognosis of early-onset pre-eclampsia.

Methods: Patients with pre-eclampsia (n = 133) were retrospectively selected, with clinical features and maternal uric acid, CysC, INR, and FIB levels collected. The relationship between clinical features and maternal uric acid, CysC, INR, and FIB was analyzed by Pearson's and Spearman's analyses.

View Article and Find Full Text PDF