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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366293 | PMC |
| http://dx.doi.org/10.1016/j.ekir.2022.05.003 | DOI Listing |
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College of General Education, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul 16974, Republic of Korea.
Exposure to low-dose ionizing radiation in occupational settings raises concerns about chromosomal aberrations (CAs) and their potential impact on genomic stability. Copy number variations (CNVs), structural genomic changes, influence susceptibility to environmental stressors and radiation-induced damage. This study analyzed CAs in 180 nuclear power plant workers exposed to occupational radiation and 45 controls, stratified by GSTM1 and GSTT1 CNVs.
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- The study investigates how genetic variations in oxidative stress, inflammation, and neurodevelopment affect spinal muscular atrophy (SMA) susceptibility and clinical progression, despite the strong influence of the SMN2 gene copy number.
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