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We propose a computational design framework to design the architecture of a white lighting system having multiple pixelated patterns of electric-field-driven quantum dot light-emitting diodes. The quantum dot of the white lighting system has been optimised by a system-level combinatorial colour optimisation process with the Nelder-Mead algorithm used for machine learning. The layout of quantum dot patterns is designed precisely using rigorous device-level charge transport simulation with an electric-field dependent charge injection model. A theoretical maximum of 97% colour rendering index has been achieved with red, green, cyan, and blue quantum dot light-emitting diodes as primary colours. The white lighting system has been fabricated using the transfer printing technique to validate the computational design framework. It exhibits excellent lighting performance of 92% colour rendering index and wide colour temperature variation from 1612 K to 8903 K with only the four pixelated quantum dots as primary.
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http://dx.doi.org/10.1038/s41467-022-31853-9 | DOI Listing |
Eur J Ophthalmol
September 2025
vEyes NPO, vEyes Lab, Milo, Italy.
PurposeTo introduce, describe and validate a novel, 3D-printed portable slit lamp system integrated with a macro lens-equipped smartphone, providing clinicians with a quick, easy, and effective method for obtaining high-quality clinical images.Materials and MethodsA 3D-printed portable slit lamp was developed, comprising a warm white LED light pen housed in a custom case with a biconvex lens focusing light through a 0.4 mm slit.
View Article and Find Full Text PDFDiscov Nano
September 2025
Department of Rehabilitation Medicine, Rehabilitation Medical Center, Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Immunoelectron Microscopy (IEM) is a technique that combines specific immunolabeling with high-resolution electron microscopic imaging to achieve precise spatial localization of biomolecules at the subcellular scale (< 10 nm) by using high-electron-density markers such as colloidal gold and quantum dots. As a core tool for analyzing the distribution of proteins, organelle interactions, and localization of disease pathology markers, it has irreplaceable value, especially in synapse research, pathogen-host interaction mechanism, and tumor microenvironment analysis. According to the differences in labeling sequence and sample processing, the IEM technology system can be divided into two categories: the first is pre-embedding labeling, which optimizes the labeling efficiency through the pre-exposure of antigenic epitopes and is especially suitable for the detection of low-abundance and sensitive antigens; the second is post-embedding labeling, which relies on the low-temperature resin embedding (e.
View Article and Find Full Text PDFBackground: The white cell precursor (WPC) channel of the Sysmex XN-series hematology analyzer, which is designed for blast detection, showed reduced sensitivity for blast detection in leukopenic patients undergoing chemotherapy. This study aimed to evaluate the gating region for apoptotic blasts in the WPC scattergram to enhance detection sensitivity.
Methods: NOMO-1 cells, a human acute monoblastic leukemia cell line, were treated with varying concentrations of cytarabine (0, 100, 500, and 1,000 nM) for three days to induce apoptosis.
J Sleep Res
September 2025
Department of Psychology, Mississippi State University, Mississippi State, Mississippi, USA.
Many behaviours which promote sleep overlap with the reported benefits of pet ownership. Research on pet ownership and sleep has predominately focused on co-sleeping with pets, leaving other pet ownership factors largely unexamined. The present study aimed to examine the relation between pet ownership and sleep as well as moderators and mediators of this relation.
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