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Intrapericardial paragangliomas are rare, highly vascular tumors that frequently adhere to adjacent structures and blood vessels, making surgical resection challenging. In this case series, we discuss the role of multimodality imaging and preoperative embolization in the management of 3 patients presenting with intrapericardial paragangliomas. ().
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334143 | PMC |
http://dx.doi.org/10.1016/j.jaccas.2022.04.014 | DOI Listing |
JACC Case Rep
August 2025
Department of Cardiology, University of Texas Medical Branch, Galveston, Texas, USA.
Background: Coronary artery perfusion of cardiac tumors is rare but carries diagnostic and therapeutic implications.
Case Summary: A 43-year-old incarcerated male with SDHD gene-associated hereditary paraganglioma-pheochromocytoma syndrome presented with dyspnea and leg edema. Computed tomography and cardiac magnetic resonance imaging revealed a vascular intrapericardial mass in the aortopulmonary window encasing major vessels.
JACC Case Rep
March 2024
Department of Cardiology, Sheffield Teaching Hospitals National Health Service Foundation Trust, Sheffield, United Kingdom.
Paragangliomas are rare extra-adrenal tumors originating from chromaffin cells. We discovered a large intrapericardial mass confirmed to be a primary cardiac paraganglioma encasing the left main stem coronary artery in a 38-year-old woman who presented with dyspnea and subscapular pain. Genetic predisposition related to succinate dehydrogenase A mutation was identified.
View Article and Find Full Text PDFAnn Endocrinol (Paris)
July 2024
Department of Endocrinology, Pedro Hispano Hospital, Matosinhos Local Health Unit, Rua Dr. Eduardo Torres, 4464-513 Senhora da Hora, Matosinhos, Portugal.
Indian J Radiol Imaging
July 2023
Department of Radiology, The University of Texas MD Anderson Cancer Center, Tucson, Arizona, United States.
Paragangliomas are neuroendocrine tumors of the sympathetic and parasympathetic nervous system that originate from neural crest cells. Less than 1% of paragangliomas are found in the heart, originating from intrinsic cardiac ganglia cells in the posterior wall the atria, atrioventricular groove, and along the root of the great vessels. A 10-year review of our institution's database identified nine patients who had documented intrapericardial paragangliomas.
View Article and Find Full Text PDFClin Radiol
December 2022
Department of Thoracic Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Paragangliomas are neuroendocrine tumours of the sympathetic and parasympathetic nervous systems originating from neural crest cells. Less than 1% of paragangliomas in the heart originate from intrinsic cardiac ganglia cells in the posterior wall of the atria, atrioventricular groove, and along the root of the great vessels. We describe the tumour characteristics, patient demographics, presentation, means of diagnosis, pathology correlation, management, and outcome in 11 patients with intrapericardial paragangliomas.
View Article and Find Full Text PDF