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Objectives: This was a retrospective analysis of the epidemiological features of pediatric intussusception, the effects of different management strategies and the factors affecting successful reduction.
Methods: Using our hospital database, data on pediatric intussusception from January 2019 to December 2020 were extracted for analysis, including demographic data, size of intussusception, treatment method, and effects.
Results: The number of children diagnosed with intussusception was 726 (782 episodes). In all, 394 (54.27%) of these children were male. The male to female ratio was 1.19:1. The peak of the onset age was between 3 and 4 years. In the single intussusception group, the successful reduction rate of cleansing enemas was 65.25%, that of air enemas was 95.80%, and that of B-ultrasound-guided hydrostatic enemas (B-USGHEs) was 96.04%. In the multiple intussusceptions group, the successful reduction rate of cleansing enemas was 43.9%, air enemas were 75%, and B-USGHE was 57.6%. There were no significant differences between the air enema and B-USGHE groups. The diameter and length were related factors influencing successful reduction (P ≤ 0.05). Fifty-three (7.53%) children had recurrent intussusception within 4 years, and all of them were following successful enemas. Thirty-one (3.40%) episodes were found to have spontaneously reduced. Five patients (0.7%) underwent surgery after the failure of air enemas or B-USGHE.
Conclusions: Pediatric intussusception in our region showed a sex ratio difference and age difference of onset. For single intussusceptions and multiple intussusceptions, the successful reduction rate of cleansing enemas means that some children may avoid radiation exposure. The diameter and length of intussusception were related factors influencing successful reduction in cleansing enema. There were no significant differences in successful reduction between air enemas and B-USGHE. Most recurrent intussusceptions can still be reduced, avoiding surgery.
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http://dx.doi.org/10.1097/PEC.0000000000002700 | DOI Listing |
J Dermatolog Treat
December 2025
Department of Dermatology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Objectives: Baricitinib showed efficacy for alopecia areata (AA) in clinical trials, with real-world data supporting its short-term effectiveness. However, long-term data are limited. We assessed the effectiveness and safety of baricitinib in AA patients over one year and explored predictive factors.
View Article and Find Full Text PDFEur J Vasc Endovasc Surg
September 2025
Vascular Surgery, Aortic Center, Hôpital Marie Lannelongue, Groupe Hospitalier Paris Saint Joseph, INSERM UMR_S 999, Université Paris Saclay, Paris, France. Electronic address:
Objective: The aim of this study was to evaluate the association between operative time (OT) and post-operative outcomes in complex endovascular aortic repair and to explore contributing factors to OT.
Methods: This retrospective, observational cohort study analysing data from a single centre included patients undergoing fenestrated endovascular aortic repair (FEVAR), branched endovascular aortic repair (BEVAR), or arch branched endovascular aortic repair (aBEVAR) from February 2018 to December 2024. OT was defined as the interval from first arterial access to closure.
Future Sci OA
December 2025
Clinical Research Institute, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Background: Smoking induces inflammation in the heart and intima layer of blood vessels by activating nuclear factor kappa B, which controls the transcription of immunoglobulin free light chain (FLC)-κ. FLC levels are indicative of higher mortality in the overall population and poorer prognoses in cardiovascular diseases. This study aimed to analyze the effect of smoking cessation (SC) on the levels of FLCs and markers of inflammation and heart failure.
View Article and Find Full Text PDFInt J Surg Case Rep
September 2025
Institute of Orthopedics and Traumatology, Military Hospital 175, Ho Chi Minh City, 70000, Viet Nam. Electronic address:
Introduction: Proximal humeral fracture-dislocations (PHF-D) are complex injuries, often requiring urgent intervention. However, management protocols remain unclear when anatomical reduction of the glenohumeral joint is achieved, but significant displacement of the greater tuberosity persists. The lack of consensus on whether to reclassify such injuries after reduction creates uncertainty in rehabilitation strategies.
View Article and Find Full Text PDFGraefes Arch Clin Exp Ophthalmol
September 2025
Department of Ophthalmology, Shimane University Faculty of Medicine, Shimane, Japan.
Purpose: To evaluate the impact of prostaglandin-associated periorbitopathy (PAP) severity on the surgical outcomes of trabeculectomy (LEC) and Ahmed Glaucoma Valve (AGV) implantation in patients with primary open-angle glaucoma.
Methods: In this propensity score-matched retrospective cohort study, a total of 106 eyes with uncontrolled glaucoma were included. Postoperative follow-ups were conducted at 1, 3, 6, 9, and 12 months.