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Background: Prostate Cancer screening based on manual palpation is subjective. Robotic palpation systems can objectively acquire stiffness conditions of the prostate.
Methods: A 2DoF cable driven robotic system for prostate palpation is proposed. An indirect method to estimate the contact force based on cable tension observation is presented. Kinematic models and a joint angle estimation method to determine the tip position of the probe are derived. Positioning accuracy was verified using an optical marker tracking system and by displacement measurement, respectively. The contact force estimation method was validated on silicone phantom samples.
Results: A good consistence between the estimated and measured contact force was observed. The contact force was correlated with the elastic modulus of each silicone phantom. There was also a good agreement between the theoretical and the measured tip position.
Conclusion: In the proposed palpation system, the indirect contact force estimation method is viable and holds potential for the stiffness assessment of the prostate. The tip position vital for palpation can be determined through estimated joint angles.
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http://dx.doi.org/10.1002/rcs.2435 | DOI Listing |
Arthroscopy
September 2025
AZBSC Orthopedics, Scottsdale, Arizona. Electronic address:
Medial meniscus posterior root tears (MMPRTs) are associated with severe biomechanical consequences (loss of hoop force transmission) that are broadly equivalent to a total meniscectomy. The resultant increase in contact pressures predisposes to high rates of advanced medial compartment arthritis at long-term follow-up. Repair of MMPRTs is associated with significantly better outcomes than partial meniscectomy or non-operative treatment (including improved patient reported outcome measures and delay or even avoidance of arthroplasty).
View Article and Find Full Text PDFPoult Sci
August 2025
Department of Animal Biosciences, Ontario Agricultural College, University of Guelph, Guelph, Ontario, N1G2W1 Canada; Campbell Centre for the Study of Animal Welfare, University of Guelph, Guelph, Ontario N1G2W1 Canada. Electronic address:
Laying hens possess a calcium-specific appetite that intensifies towards lights out to meet the high demands for eggshell formation and skeletal maintenance. Pecking blocks (PBs) are edible enrichments that can serve as an additional calcium source. We explored the relationships between PB preference (PBp), PB use, keel fracture status (KS), and eggshell quality.
View Article and Find Full Text PDFJ Tissue Viability
September 2025
Swedish Centre for Skin and Wound Research (SCENTR), School of Health Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden; Skin Integrity Research Group (SKINT), University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Faculty of Medicine a
Background: Incontinence-associated dermatitis (IAD) is a prevalent and distressing form of irritant contact dermatitis caused by prolonged exposure to urine and/or faeces. Not all incontinent individuals develop IAD, suggesting that additional prognostic factors contribute to its onset. The quality of empirical evidence supporting risk factors for IAD development is moderate to very low.
View Article and Find Full Text PDFJ Chromatogr A
September 2025
College of Materials & Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, China.
Synthetic cathinones (SCs) are drugs of abuse that act on the central nervous system, producing psychoactive effects similar to those of amphetamines. Their greater accessibility compared with the traditional amphetamine-type stimulants has contributed to their increasing popularity in recent years. The analysis of SCs in biological samples is essential for documenting their consumption.
View Article and Find Full Text PDFTher Innov Regul Sci
September 2025
Clinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Introduction: During the COVID-19 pandemic, regulatory and market access actions were taken to expedite the market entry of COVID-19 medicines. This study aims to (i) capture multi-stakeholder views on these actions, and (ii) provide recommendations for future-proofing routine and health-emergency frameworks.
Methods: Semi-structured interviews were conducted with policy makers/advisors (i.