Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
A new geranylated xanthone, nigrolineaxanthone AA () together with 18 known compounds (-) were isolated from latex and twig extracts of Planch. ex T. Anderson. Some of the isolated compounds were assessed for their antidiabetic activities and cytotoxicity against three cancer cell lines. Of these, compounds (IC value of 25.8 ± 0.2 µM), (IC value of 124.8 ± 0.7 µM), and (IC value of 44.4 ± 1.1 µM) exhibited the highest -glucosidase inhibitory, -amylase inhibitory, and glycation inhibition activities, respectively. Compound showed glucose consumption and glucose uptake with IC values of 14.2 ± 0.8 µM and 3.1-fold. Compound displayed cytotoxic activity against colon cancer (SW480) with an IC value of 4.3 ± 0.1 µM), while compound showed cytotoxicity against leukemic cancer (K562) with IC value of 4.4 ± 0.3 µM.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14786419.2022.2086544 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Tree Age-Related Differences in Chilling Resistance and Bark-Bleeding Physiological Responses to Chemical Component and Fiber Morphology Changes in Cell Walls of Bark.
Plants (Basel)
August 2025
Rubber Research Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
The purpose of this study was to establish the relationship between the chilling resistance of rubber trees and the bark-bleeding characteristics caused by chilling stress, considering physiological indicators in rubber tree bark, cell wall chemical components, fiber morphologies, and tensile properties. This offered a unique perspective for examining the underlying mechanisms of latex bleeding and chilling stress in . One-year-old seedlings and two-year-old twig segments in five- and twenty-one-year-old rubber trees (5YB and 21YB) were used to compare the age-mediation differences in their various parameters.
View Article and Find Full Text PDFThe genus Landolphia P.Beauv. (Apocynaceae): A comprehensive review on its ethnobotanical utilizations, pharmacology and nutritional potential.
J Ethnopharmacol
March 2023
Chair of Botany, Faculty of Biology, Faculty of Science, Technische Universität Dresden, 01062, Dresden, Germany.
Ethnopharmacological Relevance: The genus Landolphia is an important resource for African traditional medicine. Among the 60 different accepted species, nearly every plant part of the genus (bark, fruit, latex, leaf, leaf sap, root, rootbark, twig) from 13 species is utilized by traditional healers around Africa. Accordingly, many pharmacological studies (42) were performed on the most common species (11).
View Article and Find Full Text PDFXanthones from the latex and twig extracts of Planch. ex T. Anderson (Clusiaceae) and their antidiabetic and cytotoxic activities.
Nat Prod Res
March 2023
Center of Chemical Innovation for Sustainability (CIS) and School of Science, Mae Fah Luang University, Chiang Rai, Thailand.
A new geranylated xanthone, nigrolineaxanthone AA () together with 18 known compounds (-) were isolated from latex and twig extracts of Planch. ex T. Anderson.
View Article and Find Full Text PDFThe livers of rats subjected to end-to-side portacaval anastomoses were studied 3 to 5 months postoperatively by in vivo and electron microscopy. Compared with sham-operated controls, the livers of portacaval anastomoses animals contained dilated, tortuous networks of sinusoids. The velocity of blood flow in these vessels tended to be slower and more variable than controls, but always progressed toward the hepatic venules.
View Article and Find Full Text PDF