98%
921
2 minutes
20
Objective: The goal of this work is to analyze the influence of the distributions and dimensions of the coil elements and to present a method for improving the performance of the matrix gradient coil.
Methods: Three typical models (five structures in total) are presented, and a double-layer biplanar matrix gradient coil is used to install coil elements. Two metrics, namely, the role of coil elements and mutual inductance between coil elements, are proposed to assess the performance of coil systems. An optimization approach to design matrix gradient coils is introduced based on analyzing the distributions and dimensions of coil elements. The flexibility of the magnetic field generation of the designed coil structure is demonstrated by generating full third-order spherical harmonic fields and different oblique gradient fields.
Results: Matrix gradient coils with suitable distributions are capable of generating target magnetic fields. The role of coil elements quantitatively illustrates that the coil elements have different impacts on generating magnetic fields. Increasing the coil element dimension within a certain range can reduce the mutual inductance between coil elements and improve the performance of the coil system. The designed novel double-layer biplanar matrix gradient coil achieves an acceptable performance in generating different magnetic fields.
Conclusions: The proposed metrics can provide theoretical support for designing matrix gradient coils and evaluating their performance. The role of coil elements contributes to analyzing the distributions of coil elements to decrease the number of coil elements and power amplifiers. The mutual inductance between coil elements can be a reference for designing the dimensions of coil elements.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1007/s10334-022-01021-7 | DOI Listing |
Nucleic Acids Res
September 2025
Institute of Biophysics of the Czech Academy of Sciences, Královopolská 135, Brno 61200, Czech Republic.
RNA G-quadruplexes (rG4s) are emerging as vital structural elements involved in processes like gene regulation, translation, and genome stability. Found in untranslated regions of messenger RNAs (mRNAs), they influence translation efficiency and mRNA localization. Additionally, rG4s of long noncoding RNAs and telomeric RNA play roles in RNA processing and cellular aging.
View Article and Find Full Text PDFStructure
September 2025
Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON K7L 3N6, Canada. Electronic address:
Kinesin-8 motors regulate kinetochore-microtubule dynamics and control spindle length and positioning. Certain isoforms achieve this by traversing microtubules, accumulating at plus-ends, and depolymerizing terminal αβ-tubulin subunits. While the kinesin-8 motor domain is well characterized, the tail domain regions are less understood.
View Article and Find Full Text PDFChem Res Toxicol
September 2025
R&D Department, IMiracle (Shenzhen) Innovation Technology Co., Ltd., Junction of Menghai Boulevard and Binhai Avenue in Qianhai Shenzhen Hong Kong Cooperation Zone, Shenzhen 518100, China.
Nicotine lactate salt is one of the commonly used nicotine salts in electronic cigarette (e-cigarette) formulations, including products that have received Marketing Granted Orders through the FDA's Premarket Tobacco Product Application (PMTA) evaluation in the US. However, full-life cycle evaluation on nicotine lactate salt remains limited, especially its leaching reactions with heating elements and the potential to influence aerosol composition. This study investigated the chemical effects of nicotine lactate salt on e-cigarette heating coils and potential toxicological consequences of nickel (Ni) leachates using in vitro cells and animal models.
View Article and Find Full Text PDFACS Cent Sci
August 2025
Department of Environmental Toxicology, University of California Davis, Davis, California 95616, United States.
The rapidly evolving market of disposable e-cigarettes poses unknown health risks to adolescents and young adults. We report excessive emissions of toxic metallic elements in aerosols from flavored and "clear" versions of three popular products (Esco Bar, Flum Pebble, and ELF Bar), orders of magnitude higher in concentration than traditional cigarettes and other e-cigarettes. Heating coil elements (chromium (Cr), nickel (Ni)) likely leached into e-liquids and aerosols from coil degradation during use, increasing up to 1000-fold in concentration over the device life.
View Article and Find Full Text PDFJ Magn Reson
August 2025
Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN 37232, USA; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Cen
Flexible RF coils enhance patient comfort and increase filling factors, making them attractive for MRI. However, achieving first-mode resonance at 7 T for large-diameter, flexible coils remains a challenge. We present a coaxial capacitor (COCA) coil, which can be 10 cm in diameter and still operates in the first resonant mode at 298 MHz.
View Article and Find Full Text PDF