98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1164/rccm.202111-2644LE | DOI Listing |
Crit Care Explor
September 2025
Division of Pulmonary, Allergy, Critical Care, and Sleep, University of Minnesota, Minneapolis, MN.
Mean airway pressure, a monitored variable continuously available on the modern ventilator, is the pressure measured at the airway opening averaged over the time needed to complete the entire respiratory cycle. Mean airway pressure is well recognized to connect three key physiologic processes in mechanical ventilation: physical stretch, cardiovascular dynamics, and pulmonary gas exchange. Although other parameters currently employed in adults to determine "safe" ventilation are undoubtedly valuable for daily practice, all have limitations for continuous monitoring of ventilation hazard.
View Article and Find Full Text PDFRev Cardiovasc Med
August 2025
Department of Neurosciences, Institute of Human Anatomy, University of Padova, 35121 Padova, Italy.
Harlequin syndrome, also known as differential hypoxia (DH) or North-South syndrome, is a serious complication of femoro-femoral venoarterial extracorporeal membrane oxygenation (V-A ECMO). Moreover, Harlequin syndrome is caused by competing flows between the retrograde oxygenated ECMO output and the anterograde ejection of poorly oxygenated blood from the native heart. In the setting of impaired pulmonary gas exchange, the addition of an Impella device (ECPELLA configuration), although beneficial for ventricular unloading and hemodynamic support, may further exacerbate this competition and precipitate DH.
View Article and Find Full Text PDFMethodsX
December 2025
Animal Nutrition Division, ICAR-National Dairy Research Institute, Karnal-132001, India.
In vitro simulation of rumen fermentation is critical for improving feed efficiency, assessing dietary interventions, and supporting methane mitigation strategies in ruminant production systems. However, existing fermentation platforms are often expensive, technically complex, or poorly suited for long-term microbial viability under near-rumen conditions-especially in resource-limited settings. This study presents the development and validation of a modular, low-cost engineered to replicate key physiological parameters of the rumen, including temperature control (39-40 °C), continuous buffering via artificial saliva infusion, anaerobic regulation, and simulated motility through mixing pumps.
View Article and Find Full Text PDFJ Exp Biol
September 2025
Department of Biological Sciences, Binghamton University, State University of New York, Binghamton, NY 13902, USA.
Dissolved oxygen (DO) dramatically impacts the habitat use of many aquatic animals, particularly for air-breathing animals that rely on 'physical gills' for respiration while submerged. Invertebrates that use bubbles as physical gills directly uptake DO from the water for respiration. However, no vertebrate animals have yet been documented using physical gills.
View Article and Find Full Text PDFVet Anaesth Analg
July 2025
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Objective: To determine the use of Air-Test in ventilated, anaesthetized dogs for evaluating oxygen uptake and to determine its potential utility in guiding the decision to perform an alveolar recruitment manoeuvre (ARM).
Study Design: Retrospective cohort study.
Animals: A total of 25 client-owned dogs undergoing general anaesthesia.