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http://dx.doi.org/10.1097/XCS.0000000000000073 | DOI Listing |
Cureus
August 2025
Internal Medicine, Chukwuemeka Odumegwu Ojukwu University Teaching Hospital, Awka, NGA.
Stage IV prostate cancer (PCa) refers to a disease that has metastasized beyond the prostate gland to distant sites, such as bones, visceral organs, or non-regional lymph nodes. While early attempts at curative therapy were occasionally made in oligometastatic cases, current guidelines uniformly recommend palliative-intent management once true metastatic spread is confirmed. Over the past decade, treatment paradigms have shifted from androgen deprivation therapy (ADT) monotherapy to earlier intensification with combination regimens including chemo-hormonal therapy and next-generation hormonal agents to improve survival and quality of life (QoL).
View Article and Find Full Text PDFACS Omega
September 2025
College of Intelligent Science and Control Engineering, Jinling Institute of Technology, Nanjing 211169, Jiangsu, China.
State of charge (SOC) is extremely critical to the reliability of lithium-ion (Li-ion) battery utilization. In this study, a novel problem in which internal differences occurred in the battery package, causing uncertain SOC initialization of each battery unit, is solved by combining the variational theorem and the extended Kalman filter (EKF) algorithm. First, the importance of the initialized SOC setting of each unit in the battery package is proposed by determining the theoretical relationship between the initialization value and the current estimation result.
View Article and Find Full Text PDFBidens macroptera symbolizes the change of a season, marking the transition from the rainy season to autumn, heralding the new year for Ethiopians. Despite a general understanding of its geographic regions, significant gaps remain in identifying the habitat distribution and key predictor variables of Bidens macroptera through species distribution modeling (SDM) in the context of climate change. We developed an ensemble species distribution model using 2 statistical and 3 machine learning algorithms.
View Article and Find Full Text PDFEur Heart J Cardiovasc Imaging
September 2025
Bosch Health Campus, Robert Bosch Hospital, Department of Cardiology and Angiology, Stuttgart, Germany.
Aims: For many years, visual assessment has been the mainstay of detecting obstructive coronary artery disease (CAD) by stress perfusion cardiovascular magnetic resonance (S-CMR). Recently, fully automated quantitative assessment of myocardial blood flow (MBF) has been introduced. The value of MBF quantification in patients with coronary chronic total occlusion (CTO) is unknown.
View Article and Find Full Text PDFJ Natl Med Assoc
September 2025
K.E.Musgrave is a medical student, The George Washington University School of Medicine & Health Sciences, Washington, District of Columbia, USA. Electronic address:
The author examines the impact of academic medicine's rigid definition of success on the authenticity and well-being of medical students. Through a reflective analysis grounded in personal experience, the author highlights the discrepancy between institutional success metrics-such as perfect grades, prestigious publications, and competitive research grants-and the value of community advocacy, health equity work, and authentic expression. The narrative illustrates how success in medical education often adheres to an unspoken curriculum, promoting assimilation over inclusion and forcing students to choose between authenticity and conformity to advance in their careers.
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