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(SMV) is detrimental to soybean () breeding, seed quality, and yield worldwide. Improving the basic resistance of host plants is the most effective and economical method to reduce damage from SMV. Therefore, it is necessary to identify and clone novel SMV resistance genes. Here, we report the characterization of two soybean cultivars, DN50 and XQD, with different levels of resistance to SMV. Compared with XQD, DN50 exhibits enhanced resistance to the SMV strain SC7. By combining bulked-segregant analysis (BSA)-seq and fine-mapping, we identified a novel resistance locus, , spanning an approximately 207-kb region on chromosome 11 and containing 25 annotated genes in the reference Williams 82 genome. Of these genes, we identified eleven with non-synonymous single-nucleotide polymorphisms (SNPs) or insertion-deletion mutations (InDels) in their coding regions between two parents. One gene, (), harbored a frameshift mutation. encodes a multidrug and toxic compound extrusion (MATE) transporter that is expressed in all soybean tissues and is induced by SC7. Given that MATE transporter families have been reported to be linked with plant disease resistance, we suggest that is responsible for SC7 resistance in DN50. Our results reveal a novel SMV-resistance locus, improving understanding of the genetics of soybean disease resistance and providing a potential new tool for marker-assisted selection breeding in soybean.
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http://dx.doi.org/10.3389/fpls.2022.843633 | DOI Listing |
Arch Gerontol Geriatr
August 2025
School of Nursing, Jilin University, Changchun, China. Electronic address:
Background: Frailty is defined as a biological syndrome characterized by a decreased reserve and resistance to stressors. Frailty is closely related to lifestyle, and improving lifestyle can effectively reduce the incidence of frailty and related adverse events. Multi-component interventions were an effective mean of improving lifestyle, which has been validated in studies of other populations.
View Article and Find Full Text PDFBiomacromolecules
September 2025
Department of Chemistry, Chungbuk National University, Cheongju, Chungbuk 28644, Republic of Korea.
Marine biofouling poses significant economic and environmental challenges, highlighting the need for effective antifouling coatings. We report amphiphilic poly(SBMA--EGDEA) copolymer coatings that resist both marine diatom adhesion and sediment adsorption. The coatings were synthesized via surface-initiated ATRP and RAFT polymerization using hydrophilic sulfobetaine methacrylate (SBMA) and hydrophobic ethylene glycol dicyclopentenyl ether acrylate (EGDEA).
View Article and Find Full Text PDFACS Sens
September 2025
College of Chemistry, Beijing Normal University, Beijing 100875, China.
Dopamine (DA) signaling is essential for neurodevelopment and is particularly sensitive to disruption during adolescence. Protein restriction (PR) can impair DA dynamics, yet mechanistic insights remain limited due to challenges in real-time neurochemical sensing. Here, we present aptCFE, a robust implantable aptamer-based sensor fabricated via a reagent-free, 3 min electrochemical conjugation (E-conjugation) using amine-quinone chemistry.
View Article and Find Full Text PDFACS Sens
September 2025
School of Physics and Electric Engineering, Linyi University, Linyi 276000, China.
In this study, employing a 2D electrodeposition in situ assembly method, a high-performance HS sensor based on a p-n type CuO-CuFeO heterostructure ordered nanowire arrays was successfully fabricated on silicon substrates. Compared to CuO, CuO-CuFeO nanowire arrays exhibits an ideal interfacial barrier structure and higher initial resistance, with a response to 10 ppm of HS at room temperature (20 ± 3 °C) increased by 225 times and a response time reduced by over 2400 s. The sensor demonstrates exceptional sensitivity (LOD = 10 ppb; response = 234.
View Article and Find Full Text PDFHum Reprod
September 2025
Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.
Study Question: Does weight loss from a hypocaloric dietary intervention improve antral follicle dynamics in women with PCOS?
Summary Answer: During a 3-month hypocaloric dietary intervention, women with PCOS who experienced clinically meaningful weight loss showed more organized antral follicle development including fewer recruitment events, but no change in the overall frequency of selection, dominance, or ovulation.
What Is Known Already: There is a spectrum of disordered antral follicle development in women with PCOS including excessive follicle recruitment and turnover, decreased frequency of selection and dominance, and failure of ovulation. Lifestyle intervention aimed at weight loss is recommended to improve metabolic health in women with PCOS yet benefits on ovarian follicle development and ovulation are unclear.