98%
921
2 minutes
20
Koch is a polyphagous and major pest of leguminous crops causing significant damage by reducing the yield. Repeated application of synthetic insecticides for the control of aphids has led to development of resistance. Therefore, the present study aimed to screen the insecticidal activity of root/stem extracts/fractions, and pure molecules from Linnaeus against for identification of lead(s). Among root extract/fractions, the -hexane fraction was found most effective (LC = 1828.19 mg/L) against , followed by parent extract (LC = 2211.54 mg/L). Among stem extract/fractions, the -hexane fraction (LC = 1246.92 mg/L) was more effective than the water and -butanol fractions. Based on GC and GC-MS analysis, among different compounds identified in the -hexane fraction of root and stem, ethyl palmitate (known to possess insecticidal activity) was present in the highest concentration (24.94 to 52.95%) in both the fractions. Among pure molecules, pareirarineformate was found most effective (LC = 1491.93 mg/L) against , followed by cissamine (LC = 1556.31 mg/L). Parent extract and fractions of possess promising activity against aphid. Further, field bio-efficacy studies are necessary to validate the current findings for the development of botanical formulation.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838119 | PMC |
http://dx.doi.org/10.3390/molecules27030633 | DOI Listing |
Vet Res Commun
September 2025
Department of Aquaculture, Faculty of Fisheries, Cukurova University, Adana, Turkey.
This study evaluated how dietary black seed oil (Nigella sativa L.) against the diazinon waterborne toxicity on Nile tilapia (Oreochromis niloticus), focusing on growth performance, hematological and biochemical parameters as well as oxidative stress markers and histological changes. A 40-day feeding trial was carried out using four experimental groups: Group 1 (control group), Group 2 (N.
View Article and Find Full Text PDFPest Manag Sci
September 2025
National Key Laboratory of Green Pesticide, Key Laboratory of Natural Pesticide and Chemical Biology, Ministry of Education, College of Plant Protection, South China Agricultural University, Guangzhou, China.
Background: As one of the most destructive and invasive pests for various plants in China, Spodoptera frugiperda (Lepidoptera: Noctuidae) poses an enormous threat to food security and results in serious economic losses for harvesting and consumption of agricultural vegetables. To this end, indoxacarb has shown great promise as an effective insecticide against Spodoptera frugiperda. It is metabolized by insect esterases or amidases into the N-decarbomethoxy metabolite (DCJW), which is a key metabolite responsible for the insecticidal activity of indoxacarb.
View Article and Find Full Text PDFFront Public Health
September 2025
College of Medicine and Health Sciences, Arbaminch University, Arbaminch, Ethiopia.
Background: Long-lasting insecticidal nets (LLINs) are the main vector control tools and remain protective against malaria, even in the presence of high pyrethroid resistance. However, in sub-Saharan Africa, the estimated percentage of the population sleeping under LLINs is low. Hence, this qualitative study was conducted to explore perceptions about LLINs and the reasons for low LLIN use in southern Ethiopia.
View Article and Find Full Text PDFJ Parasitol Res
August 2025
Department of Biology, Wachemo University, Hossana, Ethiopia.
Environmental changes due to global warming and human activities have negatively impacted malaria vector control in Hadiya zone, Ethiopia. Plants contain anthraquinoes. Flavonoids, glycosides, phenol, saponin, steroids, tannin, and terpenes that are target specific, rapidly biodegradable, ecofriendly, and less toxic to human health.
View Article and Find Full Text PDFProtein Pept Lett
September 2025
Center for Advanced Therapeutics, Institute of Molecular Biosciences, Mahidol University, Salaya Campus, Nakornpathom 73170, Thailand.
Background: Bacillus thuringiensis Cry toxins are well known for their insecticidal properties, primarily through the formation of ion-leakage pores via α4-α5 hairpins. His178 in helix 4 of the Cry4Aa mosquito-active toxin has been suggested to play a crucial role in its biotoxicity.
Objective: This study aimed to investigate the functional importance of Cry4Aa-His178 through experimental and computational analyses.