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Malignant mixed mullerian tumor (MMMT) occurs rarely extragenital sites and generally originates from female genital tracts such as the uterus. Here, we report a patient with a primary MMMT of the peritoneum in a 64-year-old woman, who experienced a discontinuous epigastric pain and an abdominal distention for 3 months. An ultrasound-guided fine needle aspiration biopsy (FNA) was executed and indicated a highly malignant soft tissue sarcoma. And after that, the patient received a tumor resection (cytoreductive surgery) and postoperative chemotherapy. The postoperative immunohistochemical analysis revealed a MMMT in peritoneum. Up to now, the patient has survived for 5 months.
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http://dx.doi.org/10.21037/tcr.2019.05.07 | DOI Listing |
Int J Gynecol Cancer
August 2025
Northwell Health, Zucker School of Medicine at Hofstra/Northwell, Long Island Jewish Medical Center, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, New Hyde Park, NY, USA; Northwell Health, Feinstein Institutes for Medical Research, Institute of Molecular Medicine, Manhas
Objective: The purpose of this study was to evaluate whether the combination of cefazolin or a second-generation cephalosporin plus metronidazole is associated with a reduced risk of surgical site infection in women undergoing hysterectomy for gynecologic cancer compared to using cefazolin or a second-generation cephalosporin alone.
Methods: This was a retrospective cohort study of patients who underwent hysterectomy at a single institution between January 2020 and June 2022. The primary outcome was surgical site infection.
Carbohydr Polym
November 2025
College of Smart Agriculture (Research Institute), Xinjiang University, Urumqi 830017, China. Electronic address:
Oligosaccharides are increasingly valuable for preparing noble metal (NM) nanoparticles (NPs) due to excellent biocompatibility and abundant reducing functional groups (e.g., hydroxyl, amino, and aldehyde groups).
View Article and Find Full Text PDFPLoS One
September 2025
Maternal, Child and Nutrition Department, Bolosso Bombe District Health Office, Bombe, Ethiopia.
Background: Human papillomavirus (HPV) vaccination is a well-established global strategy for the prevention of cervical cancer. However, the uptake of the vaccine varies across regions and countries due to several factors. Although girls are at risk for cervical cancer, there are limited studies measuring vaccination uptake among female adolescents in the study area.
View Article and Find Full Text PDFFam Cancer
September 2025
Ambry Genetics, 1 Enterprise, Aliso Viejo, CA, 92656, USA.
Pathogenic variants in the APC gene are classically associated with autosomal dominant familial adenomatous polyposis (FAP), characterized by tens-to-thousands of colonic adenomatous polyps and a high-penetrance predisposition to colorectal cancer. More recently, specific PVs in the YY1 binding motif of APC promoter 1B have been associated with autosomal dominant gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS), characterized by tens-to-thousands of fundic gland polyps and a predisposition to gastric cancer but which are only rarely associated with features consistent with FAP. Although management guidelines currently treat FAP and GAPPS as mutually exclusive conditions, the extent of phenotypic overlap is not well-characterized.
View Article and Find Full Text PDFFront Oncol
August 2025
Department of General Surgery, Fourth People's Hospital of Jinan, Jinan, China.
Introduction: Clinical case reports of rectal mixed neuroendocrine-non-neuroendocrine tumors are rare. This report highlights a case in which only the neuroendocrine carcinoma component metastasized to the lymph nodes seven years postoperatively, and its successful treatment.
Case Description: A 73-year-old male was admitted to our hospital in November 2015 with rectal bleeding lasting more than four months.