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Background: This retrospective study aimed to compare the clinical outcomes of patients with staged and simultaneous bilateral total knee arthroplasty (TKA).
Methods: The present study included 100 patients with a mean age of 62±3.72 years from 2014 to 2017. Among them, 51 and 49 patients underwent simultaneous and staged bilateral TKA, respectively. The two groups were compared regarding the range of motion (ROM), Oxford Knee Score (OKS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) improvement, and Medical Outcomes Study 36-item Short-Form Health Survey (SF-36) scores. The mean follow-up duration was 24 months (range: 12-36 months).
Results: According to the results obtained from the SF-36 questionnaire (possessing eight different factors of quality of life), there was no significant difference between the two groups. Furthermore, the OKSs were 39.98±1.52 and 38.68±2.55 in the simultaneous and staged groups, respectively. Moreover, the WOMAC improvement scores were obtained at 84.15±2.2 and 83.26±2.6 in the simultaneous and staged groups, respectively. The final knee ROM was acceptable without a significant difference between the two groups.
Conclusion: Substantial controversy about the complications, functional, and clinical outcomes has negatively affected the decision of the surgeons on conducting bilateral sequential TKA. This clinical assessment revealed that all determinants, including OKS, WOMAC, SF-36, ROM, postoperative bleeding, and hospitalization duration exhibited almost the same improvement in both groups. According to this study, no statistically significant difference exists in both procedures.
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http://dx.doi.org/10.22038/ABJS.2021.48053.2379 | DOI Listing |
Environ Int
September 2025
School of Atmospheric Sciences, Nanjing University, Nanjing 210023, China.
Sichuan Basin (SCB) is a critical region in China facing the dual pressures of air pollution and population aging. This study constructed high resolution (1 km) PM datasets for SCB using advanced machine learning approaches - Super Resolution Generative Adversarial Networks (SRGAN) and Convolutional Neural Network - Long Short-Term Memory (CNN-LSTM). Evaluation results demonstrate good performance of the machine learning model (SRGAN: R = 0.
View Article and Find Full Text PDFInt J Radiat Oncol Biol Phys
September 2025
Department of Oncology and Radiotherapy, Medical University of Gdańsk, Smoluchowskiego 17 str., 80-215, Gdańsk, Poland.
Background: Stereotactic Ablative Radiotherapy (SABR) for early-stage non-small cell lung cancer (NSCLC) can stimulate an immune response against cancer. We evaluated changes in peripheral lymphocyte subpopulations and cytokines levels after SABR in patients with early-stage NSCLC. We examined how these changes relate to overall survival (OS) and disease-free survival (DFS).
View Article and Find Full Text PDFInt J Med Microbiol
September 2025
Center for Infectious Diseases and Pathogen Biology, The First Hospital of Jilin University, Jilin University, Changchun, Jilin 130000, China; Research Institute of Virology and AIDS research, The First Hospital of Jilin University, Jilin University, Changchun, Jilin 130000, China. Electronic addres
The emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) as the causative agent of COVID-19 precipitated a global health crisis of unprecedented scale. SARS-CoV-2 has been shown to interfere specifically with S phase progression during early stages of infection. Nucleocapsid (N) is an important structural protein.
View Article and Find Full Text PDFColloids Surf B Biointerfaces
August 2025
School of Stomatology, Qingdao University, Qingdao 266023, PR China; Department of Orthodontics, The Affiliated Hospital of Qingdao University, Qingdao 266003, PR China.
White spot lesions (WSLs) are the most common complication of orthodontic treatment, compromising dental health and significantly affecting aesthetics. To address this clinical challenge, this study aims to develop a dual-functional therapeutic strategy that simultaneously promotes the remineralization of demineralized enamel and inhibits the activity of cariogenic bacteria, thereby achieving effective prevention and treatment of WSLs. A hollow double-shell structured CuO@N/C nanozyme (H-CuO@N/C) was synthesized using a one-step hydrothermal method.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
September 2025
Department of Gastrointestinal Surgery, The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei 434023, PR China; Department of Laboratory Medicine, School of Medicine, Yangtze University, Jingzhou 434023, PR China. Electronic address:
Hepatic carcinoma is one of the most common malignancies with low survival rates due to insufficient therapeutics while early detection of hepatic tumors remains key to reducing mortality of liver cancer. However, current clinical methods are hard to detect pathological changes in early-stage cases while the detection rate of liquid biopsy-based assay is limited. Thus, effective tools for accurate and sensitive detection of hepatic tumors are still in urgent need.
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