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Köklü, Y, Köklü, Ö, Işıkdemir, E, and Alemdaroğlu, U. Effect of varying recovery duration on postactivation potentiation of explosive jump and short sprint in elite young soccer players. J Strength Cond Res 36(2): 534-539, 2022-The purpose of this study was to investigate the effects of postactivation potentiation (PAP) on vertical jump and sprint performances with different recovery durations. Twelve elite young soccer players (average age: 17.0 ± 0.6 years; body mass: 67.0 ± 5.4 kg; height: 175.0 ± 3.5 cm) voluntarily performed countermovement jump (CMJ) and 30-m sprints (with 10-m split times) under unloaded and 4 different recovery duration conditions (R1: 1 minute, R2: 2 minutes, R3: 3 minutes, and R4: 4 minutes) after a set of 3 repetitions of half-squat exercises at 90% of 1-repetition maximum. Electromyographic assessments of both limbs' vastus lateralis (VL) and semitendinosus (ST) muscle activity were also made during the tests. Vertical jump height, sprint time, and VL and ST muscle activity root mean square (RMS) values were analyzed. The results show that players demonstrated significantly better CMJ, 10-, and 30-m sprint performances in the R4 condition compared with the unloaded condition (p < 0.05). The players also showed significantly higher RMS values for VL and ST muscle activity in the CMJ and 30-m test performances for both legs in the R4 condition compared with the unloaded, R1, R2, and R3 conditions (p < 0.05). According to these results, if sports scientists and coaches desire to increase the PAP effect after heavy resistance training, 4 minutes of recovery time instead of 1, 2, or 3 minutes for CMJ, 10-, and 30-m sprint performances is recommended.
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http://dx.doi.org/10.1519/JSC.0000000000003435 | DOI Listing |
Drug Des Devel Ther
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Department of Anesthesiology, The Affiliated Women and Children's Hospital of Ningbo University, Ningbo, Zhejiang, People's Republic of China.
Background: Emergence delirium (ED) is a common postoperative complication during the recovery period in pediatric anesthesia. Continuous intravenous infusion of remimazolam can effectively prevent the occurrence of ED. However, the optimal dose for preventing ED in pediatric patients remains unclear.
View Article and Find Full Text PDFCureus
August 2025
Pharmacology, Indira Gandhi Institute of Medical Sciences, Patna, IND.
Background Delirium and sleep disturbances are common in critically ill patients and are associated with adverse outcomes, including prolonged intensive care unit (ICU) stays. Ramelteon, a melatonin receptor agonist, may improve sleep and reduce delirium by regulating circadian rhythms. This study evaluated the efficacy of ramelteon in shortening ICU stay, decreasing delirium incidence and duration, and improving sleep quality in critically ill patients.
View Article and Find Full Text PDFBackgroundRAY1216 is an alpha-ketoamide-based peptide inhibitor of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) major protease (M). This study evaluated the absorption, distribution, metabolism and excretion of [C]-labelled RAY1216 by oral administration.Research design and methodsThis phase Ι study was designed to assess the pharmacokinetics, mass balance and metabolic pathways in 6 healthy Chinese adult men after a single fasting oral administration of 240 mL (containing 400 mg/100 μCi) [C] RAY1216.
View Article and Find Full Text PDFEnviron Int
September 2025
State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital of Xiamen University, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian 361102, China. Electronic address:
Metabolic-associated fatty liver disease (MAFLD), linked to lipid dysregulation, poses global health risks. 2,2',3,4,4',5'-hexachlorobiphenyl (PCB138) is a persistent organic pollutant that poses potential threats to liver health due to its environmental persistence and bioaccumulation. Theabrown (TB), a natural compound extracted from black tea, exhibits lipid-lowering and antioxidant properties, but its protective effects on PCB138-induced liver injury have not been thoroughly investigated.
View Article and Find Full Text PDFDiabetes Obes Metab
September 2025
Diabetes Care Unit, Nancy University Hospital, Nancy, France.
Aims: To assess the frequency and management of hypoglycaemia during unstructured physical activity (PA) in adults with type 1 diabetes (T1D) using automated insulin delivery (AID) systems in real-life settings.
Materials And Methods: RAPPID is a prospective, multicenter, observational study conducted over 1 month in four French tertiary care centres. Adults with T1D using one of three AID systems (MiniMed 780G, Tandem t:slim X2 with Control-IQ, or Ypsopump with CamAPS FX) and performing ≥2 unstructured PA sessions per week were included.