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http://dx.doi.org/10.1136/gutjnl-2021-326484 | DOI Listing |
Front Cardiovasc Med
August 2025
Departments of Cardiology, The Second Hospital of Dalian Medical University, Dalian, Liaoning, China.
Objective: This study aims to investigate the relation of inflammatory markers to the long-term prognosis of patients with severe non-ST-segment elevation myocardial infarction (NSTEMI) in the intensive care unit (ICU), and to further develop a predictive model for their long-term outcomes.
Methods: This study utilized data on eligible NSTEMI patients from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. Patients were grouped based on mortality outcomes.
Front Med (Lausanne)
August 2025
Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Background: Intestinal barrier dysfunction (IBDF) can lead to systemic inflammatory response syndrome and multiple organ failure, severely jeopardizing patient health. Preventing the occurrence of IBDF is crucial, but effective prediction and assessment tools are currently lacking. In this study, we aimed to construct and validate a nomogram for early prediction of the risk of IBDF in patients undergoing major abdominal surgery.
View Article and Find Full Text PDFCNS Neurosci Ther
September 2025
Department of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Aims: The tissue window is increasingly recognized in guiding reperfusion therapy beyond the standard time window in acute ischemic stroke (AIS). This study aims to develop a nomogram incorporating an ischemic core growth rate index to provide individualized prediction of neurological outcomes in AIS patients who received intravenous thrombolysis (IVT).
Methods: A retrospective study was conducted at the First Affiliated Hospital of Soochow University (2016-2023).
J Inflamm Res
August 2025
Breast Surgery Unit 1, Guangxi Medical University Cancer Hospital, Nanning, Guangxi Zhuang Autonomous Region, People's Republic of China.
Purpose: This study aimed to investigate the expression of tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in postoperative patients with hepatocellular carcinoma (HCC), its relationship with prognosis, and to build a nomogram prediction model for overall survival (OS) and disease-free survival (DFS) based on TIMP-2 expression.
Patients And Methods: Expression profile data from HCC-related datasets were obtained from the Gene Expression Omnibus to analyze the correlation between TIMP-2 and HCC survival and prognosis, and its relationship with the HCC tumor immune microenvironment. Overall, 118 patients who underwent radical surgery for HCC were included retrospectively.
Front Endocrinol (Lausanne)
September 2025
School of Public Health, Lan Zhou University, Lanzhou, China.
Background: Type 2 diabetes mellitus (T2DM) is a common comorbidity of chronic obstructive pulmonary disease (COPD), which significantly increases the risk of rehospitalization and mortality in patients with COPD. Therefore, the purpose of this study was to identify the influencing factors of COPD complicated by T2DM and to construct a visualized disease prediction model.
Method: We included the medical records of 1,773 patients with COPD treated at Quzhou People's Hospital from 2020 to 2023.