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Holography exploits the interference of a light field reflected/transmitted from an object with a reference beam to obtain a reconstruction of the spatial shape of the object. Classical holography techniques have been very successful in diverse areas such as microscopy, manufacturing technology, and basic science. However, detection constraints for wavelengths outside the visible range restrict the applications for imaging and sensing in general. For overcoming these detection limitations, we implement phase-shifting holography with nonclassical states of light, where we exploit quantum interference between two-photon probability amplitudes in a nonlinear interferometer. We demonstrate that it allows retrieving the spatial shape (amplitude and phase) of the photons transmitted/reflected from the object and thus obtaining an image of the object despite those photons are never detected. Moreover, there is no need to use a well-characterized reference beam, since the two-photon scheme already makes use of one of the photons as reference for holography.
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http://dx.doi.org/10.1126/sciadv.abl4301 | DOI Listing |
Braz Oral Res
September 2025
Ankara University, Faculty of Dentistry, Department of Oral and Maxillofacial Radiology, Ankara, Turkey.
The aim of this in-vitro study was to verify which field of view (FOV) in cone-beam computed tomography (CBCT) yields greater accuracy in the detection of internal root resorption (IRR) volume, in comparison to the gold standard of micro-computed tomography (micro-CT) and to a physical method. Twenty-five extractedsingle-rooted teeth were scanned by CBCT with two different FOV parameters (6x6-FOV and 10x10-FOV) and via micro-CT. The volume of dental hard tissue was measured on these images.
View Article and Find Full Text PDFMed Phys
September 2025
Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
Background: Radiotherapy workflows conventionally deliver one treatment plan multiple times throughout the treatment course. Non-coplanar techniques with beam angle optimization or dosimetrically optimized pathfinding (DOP) exploit additional degrees of freedom to improve spatial conformality of the dose distribution compared to widely used techniques like volumetric-modulated arc therapy (VMAT). The temporal dimension of dose delivery can be exploited using multiple plans (sub-plans) within one treatment course.
View Article and Find Full Text PDFIEEE Trans Med Imaging
September 2025
Computed Tomography (CT) to Cone-Beam Computed Tomography (CBCT) image registration is crucial for image-guided radiotherapy and surgical procedures. However, achieving accurate CT-CBCT registration remains challenging due to various factors such as inconsistent intensities, low contrast resolution and imaging artifacts. In this study, we propose a Context-Aware Semantics-driven Hierarchical Network (referred to as CASHNet), which hierarchically integrates context-aware semantics-encoded features into a coarse-to-fine registration scheme, to explicitly enhance semantic structural perception during progressive alignment.
View Article and Find Full Text PDFJCO Clin Cancer Inform
August 2025
Telperian, Austin, TX.
Purpose: Lymphocytes play critical roles in cancer immunity and tumor surveillance. Radiation-induced lymphopenia (RIL) is a common side effect observed in patients with cancer undergoing chemoradiation therapy (CRT), leading to impaired immunity and worse clinical outcomes. Although proton beam therapy (PBT) has been suggested to reduce RIL risk compared with intensity-modulated radiation therapy (IMRT), this study used Bayesian counterfactual machine learning to identify distinct patient profiles and inform personalized radiation modality choice.
View Article and Find Full Text PDFJ Dent
September 2025
Maxillofacial Prosthodontist, Surgical Prosthodontist Private Practice Fort Lee, NJ, and Manhattan, New York, USA. Electronic address:
Objectives: Precise implant placement in the anterior and posterior maxilla often presents challenges due to variable bone and soft tissue anatomy. Many clinicians elect a freehand surgical approach because conventional surgical guides may not always be easy to design, fabricate, or utilize. Guided surgery has been proven to have advantages over freehand surgical protocols and therefore, the present study proposed utilizing the nasopalatine canal (NPC) as an anatomical reference and point of fixation for a novel rotational path surgical template during computer-aided implant surgery (CAIS).
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