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Introduction: A comprehensive comparison of the performance of different femoral stem geometries in total hip arthroplasty (THA) is yet to be described. The primary aim of this study was to evaluate objective and subjective outcome measures in primary THA with different femoral implant styles.
Methods: Stems were classified into the following five classes: cemented, conical, fit and fill, modular, and wedge. The objective outcomes of interest were the length of inpatient hospital stay (LOS), 90-day readmission rate, one-year revision rate, and two-year mortality rate. Preoperative and postoperative patient-reported outcome measures (PROMs), including hip disability and osteoarthritis outcome score (HOOS) - physical function shortform (HOOS-PS), patient-reported outcomes measurement information system physical function short form 10a (PROMIS PF-10a), and patient-reported outcomes measurement information system - short form - mental 10a (PROMIS M-10a) were recorded and compared between different classes.
Results: Patients with a wedge stem had a significantly lower LOS versus every other stem group, while patients with a cemented stem had the highest LOS, approximately twofold that of the wedge stem group. Accounting for potential confounders, the conical and fit and fill groups had a significantly higher two-year mortality rate than the wedge stem group. Fit and fill stems conferred a slight risk of revision THA at one-year compared to wedge stems. There was no significant difference in the rates of failure to achieve the minimal clinically important difference (MCID) for the PROMs.
Conclusion: Placement of wedge stems resulted in a significantly lower LOS compared to every other stem class and a lower mortality rate than the conical, fit and fill, and modular stems. As for the 90-day readmission, one-year revision, and the rates of failure to achieve the MCID for general or hip-specific PROMs, stem design had no meaningful effect.
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http://dx.doi.org/10.7759/cureus.19745 | DOI Listing |
Front Surg
August 2025
Department of Orthopedics, The First Hospital of Jilin University, Changchun, Jilin, China.
Background: Acetabular reconstruction is often challenging in revision hip arthroplasty, especially in the face of moderate to severe acetabular bone deficiency. In some severe bone defects, double-metal tantalum cups can improve the contact area between bone and implants, increase the surface area for bone ingrowth, and better restore the anatomical position of the acetabulum. Furthermore, with a good press-fit, the auxiliary screw has a minimal effect on acetabular cup stability.
View Article and Find Full Text PDFPsychol Assess
September 2025
Department of Special Needs Education, Gent University.
Several assessment tools have been developed to assess psychopathic traits in childhood and adolescence. However, knowledge on the continuity and change in psychopathic traits remains limited, especially because of uncertainties regarding the capacity of these tools to assess these traits using a common metric across development. To fill this void, this study tested the measurement invariance of the Child Problematic Traits Inventory (CPTI), a teacher-rated scale designed to assess psychopathic traits from ages 3 to 12 years.
View Article and Find Full Text PDFJ Biochem Mol Toxicol
September 2025
Department of Molecular Biology and Genetic Engineering, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab, India.
Epilepsy is a chronic neurological disease marked by repeated seizures due to excessive neuronal activity, frequently linked to oxidative stress. Treatment in epilepsy involves chronic use of antiseizure drugs (ASDs) which further exacerbates oxidative stress. Given its role in epilepsy, oxidative stress has been a target for therapeutic intervention, with antioxidants being explored as potential agents to mitigate oxidative damage.
View Article and Find Full Text PDFEnviron Pollut
August 2025
Laboratório de Ecologia Aplicada à Conservação, Programa de Pós-Graduação em Ecologia e Conservação da Biodiversidade, Universidade Estadual de Santa Cruz, Ilhéus, Bahia, Brazil. Electronic address:
Environmental pollution is a significant driver of biodiversity loss. Numerous synthetic chemicals, including heavy metals, are introduced into ecosystems with largely unknown impacts on wildlife. Heavy metals are a critical group of environmental pollutants due to their persistence and toxicity.
View Article and Find Full Text PDFJ Phys Chem A
August 2025
Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland 21218, United States.
Polymer-networked nanoparticles are a promising alternative to silicon semiconductors for the realization of neuromorphic computing platforms. Variations in the interaction between gold nanoparticles (AuNPs) and polyelectrolyte linkers lead to the controlled formation of engineered nanoparticle network (ENPN) structures exhibiting a broad range of topologies and dynamics. Using dissipative particle dynamics (DPD) simulations, we designed triblock copolymers with polyelectrolyte ends that can selectively attach to each of two AuNPs and bridged them together through a middle polymer segment (or block).
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