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Background: Attention-deficit/hyperactivity disorder (ADHD) in adulthood, with an estimated prevalence of 2-3%, is associated with several challenges in daily life functioning. The availability of evidence-based psychological interventions for adults with ADHD is still poor. Interventions delivered over the Internet on smartphones or personal computers may help to increase the availability of effective psychological interventions. The primary aim of this randomized controlled trial is to examine the efficacy of a self-guided Internet-delivered intervention on severity levels of ADHD symptomatology and quality of life.
Methods: We aim to include 118 participants with a self-reported ADHD diagnosis in a randomized controlled trial with two arms: 1) self-guided Internet-delivered intervention for coping with ADHD ( = 59); 2) self-guided online psychoeducation (control group, N = 59). After 3 months, the control group will be given access to the intervention. The primary clinical outcomes are inattention and quality of life. Secondary clinical outcomes are hyperactivity, stress and depression. Measures will be obtained at three time points: before (baseline), immediately after (8 weeks) and 3 months after the intervention. Uptake, usage, adherence and satisfaction will be explored.
Discussion: This RCT will provide valuable information on the clinical effectiveness of an Internet-delivered intervention for adults with ADHD. This study is, to our knowledge, one of the first randomized control trials that investigates the effects of a self-guided Internet-delivered psychological intervention in a fairly large group of adults with ADHD.
Trial Registration: ClinicalTrials.gov, Identifier NCT04726813, January 27, 2021.
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http://dx.doi.org/10.1016/j.invent.2021.100485 | DOI Listing |
Telemed J E Health
July 2025
Wolfson Institute of Population Health, Unit for Psychological Medicine, Centre for Psychiatry and Mental Health, Queen Mary University of London, London, United Kingdom.
: Internet-delivered cognitive behavioral therapy (iCBT) has become a promising alternative to face-to-face CBT, yet its long-term effectiveness across psychiatric disorders remains unclear. While numerous studies have examined short-term outcomes, it is essential to understand how iCBT compares with traditional CBT over extended periods and which conditions benefit most. : A systematic search of PubMed, Embase, MEDLINE via EBSCO, PsycINFO via APA, Scopus, and Cochrane Library (CENTRAL) was conducted up to May 21, 2025.
View Article and Find Full Text PDFPost Reprod Health
June 2025
Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
ObjectiveThe most frequently reported menopausal symptoms are hot flushes and night sweats (HFNS). This study evaluated the feasibility, and generated preliminary data on the efficacy, of a self-guided, internet-delivered Cognitive Behaviour Therapy (iCBT) program for HFNS in working menopausal women.MethodsParticipants were UK employees who accessed the iCBT program via an Employee Assistance Program.
View Article and Find Full Text PDFSubst Use Misuse
September 2025
Centre for Addiction and Mental Health, Campbell Family Mental Health Research Institute, Toronto, Ontario, Canada.
Substance use disorders (SUD) are debilitating conditions that frequently co-occur with other mental disorders. Internet-delivered dialectical behavior therapy (iDBT) skills training may be promising for SUD; however, little research has examined predictors of engagement and treatment outcome. This is a secondary, exploratory analysis of a randomized, waitlist-controlled trial of self-guided iDBT for SUD.
View Article and Find Full Text PDFFront Psychiatry
May 2025
Department of Psychiatry, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
Background: Chronic insomnia disorder (CID) is highly prevalent and impacts individuals' physiological, psychological and social functions. Although cognitive behavioral therapy for insomnia (CBT-I) is the recommended first-line treatment option for CID, approximately 20% of patients still exhibit limited effectiveness. The literature has shown that mindfulness can benefit CBT-I protocols and that mindfulness-based cognitive therapy (MBCT) is effective in treating insomnia.
View Article and Find Full Text PDFFront Psychiatry
March 2025
Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Unlabelled: The high prevalence of chronic pain and comorbid depression, along with their negative impacts on individuals and society, highlights the need for accessible and effective interventions. This study examined the feasibility, efficacy, and acceptability of Lenio, an Internet-based self-help intervention, combined with the COGITO smartphone application for managing these conditions. The randomized controlled trial involved an intervention group (IG) using Lenio and COGITO, an active control group (ACG) using a transdiagnostic app, and a wait-list control group (WCG) receiving usual treatment.
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