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Background: Chronic insomnia disorder (CID) is highly prevalent and impacts individuals' physiological, psychological and social functions. Although cognitive behavioral therapy for insomnia (CBT-I) is the recommended first-line treatment option for CID, approximately 20% of patients still exhibit limited effectiveness. The literature has shown that mindfulness can benefit CBT-I protocols and that mindfulness-based cognitive therapy (MBCT) is effective in treating insomnia. However, the effectiveness of therapist-guided internet-based MBCT-I (iMBCT-I) has not yet been tested.
Objective: This study protocol aims to evaluate the effect of therapist-guided iMBCT-I on chronic insomnia among Chinese adults.
Methods: This will be a two-armed, parallel group, randomized controlled study with 80 CID patients. The participants will be randomized to either the iMBCT-I program or the sleep hygiene education (SHE) program at an allocation ratio of 1:1 via simple randomization. Assessments will be carried out at baseline, at the end of the intervention (week 8) and at the follow-up time (week 20). The primary outcome was insomnia severity at week 8. Statistical analyses will follow the intention-to-treat (ITT) principle.
Discussion: This is the first study to investigate the effectiveness of therapist-guided iMBCT-I in CID patients. Should it be effective, this study will provide evidence for clinical practitioners, therapists and patients to consider a new psychotherapeutic option and for technicians to perform self-guided iMBCT-I applications in the future.
Clinical Trial Registration: https://www.chictr.org.cn, identifier ChiCTR240008430.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12150238 | PMC |
http://dx.doi.org/10.3389/fpsyt.2025.1506183 | DOI Listing |
J Nephrol
September 2025
Department of Psychology, Institute of Psychiatry, Psychology & Neuroscience, Health Psychology Section, King's College London, 5th Floor Bermondsey Wing, Guy's Campus, London Bridge, London, SE1 9RT, UK.
Background: Depression and anxiety are common in chronic kidney disease (CKD) and worsen clinical outcomes. Psycho-behavioural interventions offer a promising, non-pharmacological approach. However, most evidence comes from people with kidney failure with distinct treatment needs, limiting relevance to earlier stages of CKD, where timely support may enhance self-management and slow progression.
View Article and Find Full Text PDFGlob Ment Health (Camb)
July 2025
School of Social Sciences, College of Humanities, Arts, and Social Sciences, Nanyang Technological University, Singapore.
The global prevalence of mental health disorders among youths aged 15 to 24 is a significant public health concern. This systematic review aimed to explore global strategies for promoting mental well-being and addressing mental health challenges within this demographic, as defined by the World Health Organization. A comprehensive search of electronic scientific databases was conducted on November 1, 2023, yielding 43 studies with a total of 29,581 participants published between 2008 and 2023 that examined mental health interventions targeting youth.
View Article and Find Full Text PDFAppl Neuropsychol Adult
September 2025
Psychiatry Department, Mashhad University of Medical Sciences Mashhad, Iran.
Ischemic stroke survivors often experience persistent cognitive and psychosocial deficits not fully addressed by conventional rehabilitation. This study compared the effectiveness of Mindfulness-Based Stress Reduction (MBSR) and Cognitive Rehabilitation Therapy (CRT) on Stroke Impact Scale (SIS) outcomes. In a quasi-experimental design with a control group and follow-up, 45 eligible patients were purposively sampled and randomly assigned to MBSR, CRT, or control groups.
View Article and Find Full Text PDFSci Rep
September 2025
Department of Data Science, Hanyang University, Seoul, 04763, Republic of Korea.
The increasing prevalence of depression has highlighted Mindfulness-Based Cognitive Therapy (MBCT) as an effective treatment. However, conventional MBCT has several limitations, including barriers to access, the need for trained professionals, and inconsistent levels of participant engagement. The feasibility of using Virtual Reality (VR) for MBCT has emerged as a promising solution, but further research is needed to assess its therapeutic potential.
View Article and Find Full Text PDFInt J Clin Oncol
September 2025
Institute for Applied Research in Public Health, School of Public Health, Nantong University, Nantong, China.
Background: To evaluate the effects of cognitive-behavioral therapy (CBT) and mindfulness-based therapy (MBT), individually and in combination, on alleviating anxiety and depression, and improving quality of life (QoL) in breast cancer patients.
Methods: We searched PubMed and EMBASE for articles published up to April 6, 2025, using the keywords "randomized controlled trials (RCTs)", "cognitive-behavioral therapy", "mindfulness-based therapy", and "breast cancer". Pooled effects were expressed as standardized mean differences (SMDs) and 95% confidence intervals (CIs).