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Contaminant source identification improves the understanding of contaminant source characteristics including location and release time, which can lead to more effective remediation and water resources management plans. The backward probability model can provide probabilities of source locations and release times under various contaminant properties and hydrogeologic conditions. The backward probability model has been applied to numerous synthetic and real contamination sites for locating possible contaminant sources, but it is also important to evaluate the reliability of the backward probability model through rigorous verification analyses. Here, we present a model verification framework for the backward probability model using a stepwise approach from simple to complex model settings: comparison with previous studies, transient saturated flow under various hydrogeologic conditions, and transient variably-saturated flow conditions. As a simple condition, one-dimensional homogeneous problems under steady-state and transient flow conditions were verified by comparing with previous studies. Model verifications with complex conditions were conducted by comparing forward and backward probability simulation results. The verification results demonstrate that the backward probability model performs well for homogeneous problems. For heterogeneous problems, the backward probability model results in slightly different backward travel times due to differences in solute decay and boundary conditions assigned for both forward and backward probability simulations, but the backward travel time at the maximum probability can be reproduced well.
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http://dx.doi.org/10.1016/j.jconhyd.2021.103909 | DOI Listing |
Front Endocrinol (Lausanne)
September 2025
School of Public Health, Lan Zhou University, Lanzhou, China.
Background: Type 2 diabetes mellitus (T2DM) is a common comorbidity of chronic obstructive pulmonary disease (COPD), which significantly increases the risk of rehospitalization and mortality in patients with COPD. Therefore, the purpose of this study was to identify the influencing factors of COPD complicated by T2DM and to construct a visualized disease prediction model.
Method: We included the medical records of 1,773 patients with COPD treated at Quzhou People's Hospital from 2020 to 2023.
PLoS One
September 2025
Institute of Pharmacy, Pharmaceutical Biology & Clinical Pharmacy, Paracelsus Medical University Salzburg, Salzburg, Austria.
Background: Drug-related problems (DRP) in pre-operative care can harm patient outcomes. This study aimed to develop and validate a pre-operative risk prediction tool (mediPORT) to calculate the probability of DRP in admitted patients.
Methods: Elective surgery patients aged ≥ 18 years admitted to the pre-anaesthesia clinic and participating in a medication review by pharmacists were included in this case-control study.
Diagn Progn Res
September 2025
Department of Clinical Epidemiology and Medical Technology Assessment (KEMTA), Maastricht University Medical Center+ (MUMC+), P.O. Box 5800, 6202, AZ, Maastricht, The Netherlands.
Background: A subset of COVID-19 patients develops post-COVID-19 condition (PCC). This condition results in disability in numerous areas of patients' lives and a reduced health-related quality of life, with societal impact including work absences and increased healthcare utilization. There is a scarcity of models predicting PCC, especially those considering the severity of the initial severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and incorporating long-term follow-up data.
View Article and Find Full Text PDFJ Am Geriatr Soc
September 2025
Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Background: For selected patients at increased fall risk, physical therapy may include instruction to look around and observe the environment to identify obstacles, known as visual scanning or tracking, and avoid them. Whether visual scanning reduces fall risk more broadly in the general population is unknown.
Methods: Using data from the Mexico Health and Aging Study (MHAS), a longitudinal, nationally representative study of adults 50 years of age and older in Mexico (n = 13,850), we measured the association between visual scanning test performance and three fall-related outcomes: any fall in the previous 2 years, recurrent falls, and falls with injury.
Front Public Health
August 2025
Department of Biochemistry, Nutrition and Health Promotion, Mississippi State University, Starkville, MS, United States.
Background: Anemia is a leading contributor to child morbidity and mortality in Sub-Saharan Africa. In Uganda, more than half of the children under 5 years are affected by anemia. Understanding context-specific determinants remains critical for targeted interventions.
View Article and Find Full Text PDF