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More consumers are being diagnosed with celiac disease or diseases in which wheat products should be avoided. For this reason, it is important to increase the range of gluten-free products available. In this study, it was decided to optimize the technology for the creation of a muffin with β-glucan (BG) and pomegranate (PG), while establishing water share (WT), using the response surface methodology. It was shown that β-glucan and water had the most significant influence on specific volume and moisture ( ≤ 0.001). However, the increase of hardness, color, and total phenolic content (TPC) was mainly influenced by the increase of pomegranate content ( ≤ 0.01 for harness and color and ≤ 0.001 for TPC). Consumers accepted products high in β-glucan more than high in pomegranate. Optimization ended with a composition that included 1.89% BG, 9.51% PG, and 77.87% WT. There were no significant differences between the model and the experimental sample, apart from higher consumer acceptability.
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http://dx.doi.org/10.3390/foods10112551 | DOI Listing |
Nutr Rev
September 2025
Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka 576104, India.
Pomegranate (Punica granatum L) is a rich source of bioactive compounds, including punicalagin, ellagic acid, anthocyanins, and urolithins, which contribute to its broad pharmacological potential. This review summarizes evidence from in vitro and in vivo experiments, as well as clinical studies, highlighting pomegranate's therapeutic effects in inflammation, metabolic disorders, cancer, cardiovascular disease, neurodegeneration, microbial infections, and skin conditions. Mechanistic insights show modulation of pathways such as nuclear factor-kappa B (NF-κB), mitogen-activated protein kinase (MAPK), alpha serine/threonine-protein kinase (AKT1), and nuclear factor erythroid 2-related factor 2 (Nrf2).
View Article and Find Full Text PDFFood Res Int
November 2025
Dairy Research Department, Food Technology Research Institute, ARC, Giza 12619, Egypt.
Domiati cheese, one of the most popular soft white cheeses, is particularly susceptible to microbial deterioration due to its high moisture content and low salt concentration. This study assesses the effectiveness of a new edible coating made from carboxymethyl chitosan nanoparticles loaded with pomegranate peel extract (CCS LP) in increasing the shelf life of Domiati cheese. The study compares CCS LP's performance to pomegranate peel extract (PPE) and carboxymethyl chitosan nanoparticles (CCS NPs) alone.
View Article and Find Full Text PDFJ Inflamm Res
September 2025
Department of Pharmacy, Hangzhou Third People's Hospital, Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, 310009, People's Republic of China.
Mitochondria play a crucial role in reactive oxygen species (ROS)-dependent rheumatic diseases, including ankylosing spondylitis, osteoarthritis (OA), systemic lupus erythematosus (SLE) and scleroderma. Mitochondrial DNA (mtDNA), which encodes mitochondrial proteins, is more vulnerable to oxidants compared to nuclear DNA. When mtDNA gets damaged, it leads to mitochondrial dysfunction, such as electron transport chain impairment and loss of mitochondrial membrane potential.
View Article and Find Full Text PDFPlant Physiol Biochem
September 2025
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, T6G 2P5, Canada. Electronic address:
Many plant-derived unusual fatty acids (UFAs) possess valuable chemical properties and have potential applications in the food, feed, and oleochemical industries. Despite significant interest, the mechanisms by which plants synthesize and accumulate these structurally distinct fatty acids remain only partially understood. While enzyme substrate specificities involved in UFA-containing storage lipid assembly have been well characterized in many prior studies, the biochemical roles of protein-protein interactions (PPIs) in coordinating UFA biosynthesis have received less attention.
View Article and Find Full Text PDFMol Nutr Food Res
September 2025
Institute of Nutrition and Health, Qingdao University, Qingdao, People's Republic of China.
Ellagic acid (EA), a bioactive polyphenol abundant in pomegranate and berries, exhibits potential in metabolic regulation. This study investigates EA's anti-obesity mechanisms, focusing on its effects on gut microbiota and transcriptional regulation in adipose tissue. After a 9-week high-fat diet feeding, mice were divided into groups and treated with low-dose EA (10 mg/kg/day), high-dose EA (30 mg/kg/day), or urolithin A (20 mg/kg/day) for 7 weeks, with healthy and obese controls included.
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