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Article Abstract
The Republic of Korea has a high incidence of tuberculosis (TB) and TB-specific mortality rate. In 2019, it had the second highest TB-specific mortality among Organization for Economic Co-operation and Development countries. Understanding the factors associated with TB-specific deaths may help eradicate the disease. Therefore, we aimed to identify the general characteristics associated with TB-specific mortality among Koreans. Using Causes of Death Statistics data from Statistics Korea, we assessed the year of death, sex, age, occupation, area of residence, marital status, and education level reported between 2008 and 2017. Patient characteristics associated with TB-specific deaths were analyzed using the Chi-squared test, while influencing factors of TB-specific mortality were analyzed using logistic regression analysis to calculate adjusted odds ratios (AOR). Female (AOR: 0.509, 95% CI: 0.493-0.526), those with a graduate degree or higher (AOR: 0.559, 95% CI: 0.474-0.660) had lower TB-specific mortality rates than those of their counterparts. Conversely, those aged ≥70 years (AOR: 1.239, 95% CI: 1.199-1.280), single (AOR: 1.355, 95% CI: 1.315-1.396), and skilled agricultural, forestry, and fishery workers (AOR: 1.441, 95% CI: 1.359-1.529) had higher TB-specific mortality rates than those of their counterparts. In conclusion, TB-specific mortality rates differed according to the characteristics of the deceased patients. In order to establish effective TB control, multisectoral action on broader determinants should be strengthened.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564039 | PMC |
| http://dx.doi.org/10.3389/fpubh.2021.691006 | DOI Listing |
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Article Synopsis
- The study investigated death rates and predictors among patients with multidrug/rifampin-resistant tuberculosis (MDR/RR-TB) in South Korea from 2011 to 2017.
- Among 7,226 cases, 699 (9.7%) died within an average of 167 days of starting treatment, with significant differences in timing between TB-related and non-TB-related deaths.
- Key factors associated with higher mortality included older age, male sex, existing health conditions, low income, and specific TB characteristics, indicating high-risk groups that need targeted intervention to reduce mortality rates.