Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
In recent years, researchers have been pursuing a method to design and to construct life forms from scratch - in other words, to create artificial cells. In many studies, artificial cellular membranes have been successfully fabricated, allowing the research field to grow by leaps and bounds. Moreover, in addition to lipid bilayer membranes, proteins are essential factors required to construct any cellular metabolic reaction; for that reason, different cell-free expression systems under various conditions to achieve the goal of controlling the synthetic cascades of proteins in a confined area have been reported. Thus, in this review, we will discuss recent issues and strategies, enabling to control protein synthesis cascades that are being used, particularly in research on artificial cells.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1042/BST20210175 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Resistance training, but not leucine, increased basal muscle protein synthesis and reversed frailty in older women consuming optimized protein intake.
Geroscience
September 2025
Research Institute of the McGill University Health Centre, 2155 Guy Street, Suite 500, Montreal, QC, H3H 2R9, Canada.
Frailty, often linked to sarcopenia, involves reduced muscle strength and mass. While sarcopenia has multiple causes, impaired muscle protein synthesis may contribute. Leucine and resistance training (RT) are anabolic stimuli, but the long-term effects of leucine combined with RT in pre/frail older women remain unclear.
View Article and Find Full Text PDFNeddylation regulates the development and function of glutamatergic neurons.
Commun Biol
September 2025
Department of Molecular Neurobiology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Neuronal development and function are orchestrated by a plethora of regulatory mechanisms that control the abundance, localization, interactions, and function of proteins. A key role in this regard is assumed by post-translational protein modifications (PTMs). While some PTM types, such as phosphorylation or ubiquitination, have been explored comprehensively, PTMs involving ubiquitin-like modifiers (Ubls) have remained comparably enigmatic (Ubls).
View Article and Find Full Text PDFFunctional divergence of NCS homologs in the PR10 family drives tissue-specific berberine accumulation in Coptis chinensis Franch.
Plant Physiol Biochem
August 2025
School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China. Electronic address:
The PR10 (Pathogenesis-Related Protein 10) family plays a crucial role in plant defense and growth regulation, with unique hydrophobic cavities that bind various ligands, including phytohormones and alkaloids. Among them, Norcoclaurine Synthases (NCS) are key enzymes in benzylisoquinoline alkaloid (BIAs) biosynthesis, catalyzing the Pictet-Spengler reaction to form the precursor (S)-norcoclaurine. However, the evolutionary origins and functions of the PR10 family in BIA biosynthesis remain unclear.
View Article and Find Full Text PDFIngestion of a lipid-rich meat matrix blunts the post-exercise increase of myofibrillar protein synthesis rates in healthy adults: A randomized controlled trial.
Am J Clin Nutr
September 2025
Department of Health and Kinesiology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA; Division of Nutritional Sciences, University of Illinois Urbana-Champaign, Urbana, Illinois, USA. Electronic address:
Background: There is considerable variation in the anabolic action of ingesting protein-dense foods on the stimulation of postprandial myofibrillar protein synthesis rates (MPS) despite ingesting similar amounts of protein and essential amino acids (EAA) OBJECTIVES: To determine the effects of consuming high-fat pork (HFP), low-fat pork (LFP), or a carbohydrate control (CHO) on the MPS response METHODS: In a semi-crossover design, sixteen physically active adults (25 ± 5 y; 25.0 ± 2.3 kg·m; 12M, 4F) received primed-constant infusions of L-[ring-C]phenylalanine and performed an acute bout of resistance exercise.
View Article and Find Full Text PDFReview of engineered magnetic chitosan nanoparticles for drug delivery: Advances, challenges, and future prospects.
Int J Biol Macromol
September 2025
Centre for Research Impact & Outcome, Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India; Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand. Electronic address:
Magnetic chitosan nanoparticles represent a promising platform in targeted drug delivery by merging the biocompatibility and mucoadhesiveness of chitosan with the superparamagnetic iron-oxide cores magnetite (Fe₃O₄) or maghemite (γ-Fe₂O₃). This synergy enables enhanced therapeutic precision through external magnetic guidance, controlled release, and stimuli-responsive behavior. MCNPs are particularly valuable in oncology, allowing site-specific drug delivery, magnetic hyperthermia, and real-time imaging via MRI.
View Article and Find Full Text PDF