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Relatively little is known about identity-related resilience factors associated with well-being among transgender and gender non-conforming (TGNC) people. Drawing upon theory on stigma-related stress and resilience and work examining group identification as a buffer against discrimination, the aim of the current study was to model perceived discrimination, transgender identification, and gender identity affirmation as predictors of well-being for TGNC people. We also tested whether the positive association between gender identity affirmation and well-being might be explained by the benefits affirmation has for individual self-concept clarity. Participants were 105 TGNC individuals (42% transgender male, 39% transgender female, 19% other gender non-conforming [e.g., non-binary]) recruited through online forums and support groups in the UK and North America who completed an online survey including self-report measures of key constructs. Results from structural equation models demonstrated that: (1) experiences of discrimination were associated with lower well-being overall, but having a stronger transgender identity moderated this association; (2) after adjustment for discrimination and transgender identification, experiences of gender identity affirmation were independently associated with greater well-being for TGNC people. Secondary analyses demonstrated that gender identity affirmation was linked to well-being through reinforcing a strong, internalized sense of clarity about individual self-concept. Results are discussed in terms of the implications for TGNC health and well-being, particularly with regard to the need for supportive, identity-affirming social environments.
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http://dx.doi.org/10.1007/s10508-021-02029-1 | DOI Listing |
JMIR Cancer
September 2025
Department of Health Outcomes and Biomedical Informatics, University of Florida, 1889 Museum Road, Suite 7000, Gainesville, FL, 32611, United States, 1 352 294-5969.
Background: Disparities in cancer burden between transgender and cisgender individuals remain an underexplored area of research.
Objective: This study aimed to examine the cumulative incidence and associated risk factors for cancer and precancerous conditions among transgender individuals compared with matched cisgender individuals.
Methods: We conducted a retrospective cohort study using patient-level electronic health record (EHR) data from the University of Florida Health Integrated Data Repository between 2012 and 2023.
PLOS Digit Health
September 2025
Department of Dermatology, Stanford University, Stanford, California, United States of America.
Large Language Models (LLMs) are increasingly deployed in clinical settings for tasks ranging from patient communication to decision support. While these models demonstrate race-based and binary gender biases, anti-LGBTQIA+ bias remains understudied despite documented healthcare disparities affecting these populations. In this work, we evaluated the potential of LLMs to propagate anti-LGBTQIA+ medical bias and misinformation.
View Article and Find Full Text PDFEvol Psychol
September 2025
Department of Psychological Sciences & Health, University of Strathclyde, UK.
Researchers have suggested that men with more masculine facial characteristics have stronger immune systems but are perceived to be less likely to invest resources in partners and offspring. How women resolve this putative trade-off between the costs and benefits of choosing a masculine mate have previously been reported to be associated with women's openness to uncommitted relationships (i.e.
View Article and Find Full Text PDFCureus
August 2025
Obstetrics and Gynaecology, Kalinga Institute of Nursing Sciences, Kalinga Institute of Industrial Technology, Deemed to be University (KIIT-DU), Bhubaneswar, IND.
Male infertility is a major health concern worldwide. While biological causes are well understood, the psychological aspects receive less focus. This gap is evident in clinical practice and research, where emotional, social, and mental health issues linked to male infertility are often neglected or inadequately managed.
View Article and Find Full Text PDFSex Res Social Policy
September 2024
Ohio State University, Columbus, USA.
Introduction: LGBTQ+ individuals are more vulnerable to experiencing sexual victimization. To truly prevent sexual victimization, preventing perpetration is necessary. The goal of this study was to increase the inclusivity of sexual violence research by examining the rates of sexual violence perpetration among cisgender, monosexual (e.
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