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Background: Bangladesh experienced a sudden, large influx of forcibly displaced persons from Myanmar in August 2017. A cholera outbreak occurred in the displaced population during September-December 2019. This study aims to describe the epidemiologic characteristics of cholera patients who were hospitalized in diarrhea treatment centers (DTCs) and sought care from settlements of Forcibly Displaced Myanmar Nationals (FDMN) as well as host country nationals during the cholera outbreak.
Methods: Diarrhea Treatment Center (DTC) based surveillance was carried out among the FDMN and host population in Teknaf and Leda DTCs hospitalized for cholera during September-December 2019.
Results: During the study period, 147 individuals with cholera were hospitalized. The majority, 72% of patients reported to Leda DTC. Nearly 65% sought care from FDMN settlements. About 47% of the cholera individuals were children less than 5 years old and 42% were aged 15 years and more. Half of the cholera patients were females. FDMN often reported from Camp # 26 (45%), followed by Camp # 24 (36%), and Camp # 27 (12%). Eighty-two percent of the cholera patients reported watery diarrhea. Some or severe dehydration was observed in 65% of cholera individuals. Eighty-one percent of people with cholera received pre-packaged ORS at home. About 88% of FDMN cholera patients reported consumption of public tap water. Pit latrine without water seal was often used by FDMN cholera individuals (78%).
Conclusion: Vigilance for cholera patients by routine surveillance, preparedness, and response readiness for surges and oral cholera vaccination campaigns can alleviate the threats of cholera.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457470 | PMC |
http://dx.doi.org/10.1371/journal.pntd.0009618 | DOI Listing |
Matern Child Health J
September 2025
Division of General Pediatrics and Adolescent Medicine, Department of Pediatrics, University of North Carolina at Chapel Hill, 231 MacNider Building, 301B S. Columbia St., Chapel Hill, NC, 27599-7225, USA.
Background And Objective: Children's healthcare providers have important roles in kindergarten readiness. We sought to understand children's primary care providers' (PCP) current approaches to fostering kindergarten readiness for their patients, perceptions of barriers, and ideas for improvement.
Methods: Children's PCPs were recruited and interviewed between June and August 2021.
BMC Public Health
September 2025
Uganda Public Health Fellowship Program, Uganda National Institute of Public Health, Kampala, Uganda.
Background: Cholera is endemic in Uganda with periodic outbreaks occurring annually. On July 24, 2023, Uganda's Ministry of Health confirmed a cholera outbreak in Sigulu Island, Namayingo District. We investigated to determine its magnitude, identify possible exposures, and recommend evidence-based control interventions.
View Article and Find Full Text PDFCureus
July 2025
Department of General Medicine and Infectious Diseases, Japan Agricultural Cooperative (JA) Toyama Koseiren Takaoka Hospital, Takaoka, JPN.
We describe a case of acute cholangitis with bacteremia caused by non-O1 and non-O139 (NOVC) in a 76-year-old man following acute gastroenteritis. The strain, isolated from blood cultures, was identified as serogroup O120. It lacked the cholera toxin gene, but it harbored multiple virulence genes, including , , , and .
View Article and Find Full Text PDFFront Immunol
September 2025
Research Division, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Background: Cholera is a public health threat in resource-limited settings and is responsible for causing over 3 million cases globally. Mucosal immune responses play an important role in protecting against infection, a non-invasive mucosal pathogen, yet traditional plasma-based assays are invasive and logistically challenging, particularly during outbreaks in low- and middle-income countries (LMICs). Saliva offers a unique window into mucosal immunity and may serve as a non-invasive alternative for seroprevalence and vaccine immunogenicity studies.
View Article and Find Full Text PDFCell Death Discov
August 2025
Department of Molecular Biology, Umeå University, Umeå, Sweden.
Recent studies reveal that Vibrio cholerae secretes virulence factors impacting host cell viability, though their effects on cancer cells remain unclear. However, the bacterial components and mechanisms influencing cancer cells remain largely unknown. This study investigated the effects of V.
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