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Each year, patients are bombarded with diverging and even contradictory reports concerning the impact of certain additives, foods, and nutrients on cardiovascular health and its risk factors. Accordingly, this third review of nutrition controversies examines the impact of artificial sweeteners, cacao, soy, plant-based meats, nitrates, and meats from grass compared to grain-fed animals on cardiovascular and other health outcomes with the goal of optimizing clinician-led diet counseling.
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http://dx.doi.org/10.1016/j.amjmed.2021.07.046 | DOI Listing |
Heart Fail Rev
September 2025
Department of Medicine, Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.
Hypoalbuminemia is commonly seen in patients with heart failure and is associated with worse outcomes. Multiple pathophysiologic mechanisms can contribute to low albumin levels in heart failure patients, such as malnutrition, hepatic congestion, inflammation, and protein-losing enteropathy. Hypoalbuminemia can exacerbate heart failure symptoms and contributes to pulmonary edema by reducing plasma oncotic pressure, thereby favoring fluid movement into the interstitial and alveolar spaces.
View Article and Find Full Text PDFJ Endocrinol Invest
September 2025
Key Laboratory of Immune Microenvironment and Inflammatory Disease Research in Universities of Shandong Province, School of Basic Medical Sciences, Shandong Second Medical University, Weifang, China.
Purposes: Controversy has emerged regarding the impact of non-nutritive sweeteners (NNS) on body weight. This systematic review and meta-analysis of randomized controlled trials aims to assess the effect of NNS intake on body weight change.
Results: Of the 3327 studies retrieved, 19 met the eligibility criteria for inclusion in the meta-analysis.
Biomed Pharmacother
September 2025
Department of Food Hygiene and Nutrition, College of Laboratory Medicine, Hunan University of Medicine, Huaihua, Hunan, China. Electronic address:
Colorectal cancer (CRC) ranks among the most prevalent malignancies globally, distinguished by its high incidence, significant mortality, and poor prognosis. Despite advancements in early screening and therapeutic strategies, clinical outcomes remain suboptimal. In recent years, autophagy has emerged as a pivotal focus in CRC research.
View Article and Find Full Text PDFCurr Opin Pediatr
October 2025
Division of Pediatric Gastroenterology, Hepatology and Nutrition, Stanford University School of Medicine and Stanford Children's Health, Palo Alto, California, USA.
Purpose Of Review: Median arcuate ligament syndrome (MALS) is understood to be a condition where compression of the celiac artery by the median arcuate ligament (MAL) may lead to symptoms of postprandial or exercise-induced abdominal pain, nausea, vomiting, diarrhea, oral aversion, and weight loss. This review summarizes recent literature on pediatric MALS while highlighting the challenges, comorbidities, and controversies encountered in this condition.
Recent Findings: The pathophysiologic mechanism by which MALS leads to pain is currently unknown.
Biol Trace Elem Res
September 2025
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, No. 155 in Nanjing North Street, Heping Distinct, Shenyang, 110001, P. R. China.
The relationship between maternal thyroid function and intellectual development of offspring is controversial. Iodine may be an important confounding factor. This study investigated whether maternal iodine status could affect the efficacy of levothyroxine (LT4) treatment during early pregnancy on the intellectual growth of progeny.
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