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Objective: Assess the relationships between case total work relative value units (wRVU), patient frailty, and the physiologic stress of surgical interventions.
Summary Of Background Data: Surgeon reimbursement is frequently apportioned by wRVU. These subjective, procedure-specific valuations generated by physician survey estimate the intensity and time for typical patient care services. We hypothesized wRVU would not adequately account for patient-specific factors, such as frailty, that modify the required physician work, regardless of procedural complexity.
Methods: Using National and Veterans Affairs Surgical Quality Improvement Programs (2015-2018), we evaluated the correlation between case total wRVU, patient frailty (risk analysis index) and physiologic surgical stress (operative stress score).
Results: Of 4,111,371 (86%) cases, the correlation between total wRVU and operative stress was moderate [ρs = 0.587 (95% confidence interval, 0.586-0.587)], but negligible with frailty ρ = 0.177 (95% confidence interval, 0.176-0.178)]. Very high operative stress procedures [n = 34,047 (1%)] generated a mean total wRVU of 55.1 (standard deviation, 12.9), comprising 7%, 2%, and 1% of thoracic, vascular, and general surgical cases, respectively. Very frail patients [n = 152,535 (4%)] accounted for 9% of thoracic, 9% of vascular, 4% of general, 5% of urologic, and 4% of neurologic surgical cases, generating 21.0 (standard deviation, 12.4) mean total wRVU. Some nonfrail patients undergoing low operative stress procedures [n = 60,128 (2%)] nonetheless generated the highest quintile wRVU; these comprised >15% of plastic, gynecologic, and urologic surgical cases.
Conclusions: Surgeon reimbursement correlates with operative stress but not patient frailty. The total wRVU does not adequately reflect patient-specific factors that increase the physician workload required to render optimal care to complex patients.
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http://dx.doi.org/10.1097/SLA.0000000000005068 | DOI Listing |
FEMS Yeast Res
September 2025
Department of Bioengineering, School of Life Science Engineering, College of Interdisciplinary Science and Technology, University of Tehran, Tehran, Iran.
The growing challenges posed by global warming and the demand for sustainable food and feed resources underscore the need for robust microbial platforms in bioprocessing. Thermotolerant yeasts have emerged as promising candidates due to their ability to thrive at elevated temperatures and other industrially relevant stresses. This review examines the industrial potential of thermotolerant yeasts in the context of climate change, emphasizing how their resilience can lead to more energy-efficient and cost-effective bioprocesses.
View Article and Find Full Text PDFInt J Surg
September 2025
Department of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Background: Phrenic nerve injury during mediastinal tumor resection can lead to significant postoperative diaphragmatic dysfunction. Current intraoperative protection techniques are imprecise and lack real-time feedback. We aimed to develop and validate a quantifiable, multimodal neuroprotective strategy.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
September 2025
Department of Ophthalmology, Tangdu Hospital, The Fourth Military Medical University, Xi'an, China.
Purpose: To explore the causal links between antihypertension drugs usage and age-related macular degeneration (AMD).
Methods: Multiple genetic analyses, including summary data-based Mendelian randomization (SMR), traditional MR, and colocalization analysis, were used to explore the causal associations between antihypertension drugs and AMD. Clinical data from the UK Biobank and the National Health and Nutrition Examination Survey (NHANES) was applied to refined risk assessment of specific antihypertensive medications in the context of AMD development.
Ann Surg
September 2025
Department of Surgery, Wake Forest University School of Medicine, Winston-Salem, NC.
Objective: The objective of this study was to systematically explore how culture has been conceptualized, investigated, and measured within general surgery residency training programs.
Summary Background Data: Research on the culture of general surgery residency training programs has primarily focused on examining individual parameters, such as mistreatment and burnout, rather than comprehensively analyzing the overall culture, climate, or learning environment.
Methods: Five databases (PubMed, Embase, Cochrane, CINAHL, APA PsycInfo) were searched.
Kaohsiung J Med Sci
September 2025
Department of Pharmacy, Ningbo Medical Center Lihuili Hospital, Ningbo, Zhejiang Province, China.
Traumatic brain injury (TBI) causes a high level of blood glutamate, which triggers host defense by activating oxidative stress and inflammation response. However, the concrete mechanism underlying its exacerbating effects on acute lung injury (ALI) severity remains unknown. In the present study, we aim to demonstrate the special role of N-methyl-D-aspartate receptor (NMDAR) in regulating glutamate-related inflammation signaling to facilitate the sustaining injury.
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