Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Our aim in this study was to compare the blood gas changes, the malondialdehyde (MDA) and endogenous antioxidant glutathione (GSH) levels in blood and lung tissues after ischemia/reperfusion, the histopathological damage in lung tissue in rats provided respiratory support with mechanical ventilation after translaryngeal intubation and tracheostomy.
Methods: Group 1 rats were provided mechanical ventilator support after translaryngeal intubation, Group 2 mechanical ventilator support after tracheostomy, and Group 3 was the control group where rats were only anesthetized. Three groups were compared for blood gas changes, MDA, GSH, and histopathological changes.
Results: Blood gas evaluation showed a more marked increase in pO2 values and decline in pCO2 values in Group 2 than Group 1 (p<0.05), and higher serum MDA levels in Group 1 than Group 2 (p<0.05). Tissue GSH levels in Groups 1 and 2 were higher than the control group, but this difference was not statistically significant (p>0.05). In terms of histopathological scoring, the damage score in Group 1 was higher than in Group 2 (p<0.05).
Conclusion: This is the first study to show tracheostomy to be more advantageous than translaryngeal intubation in terms of blood gases, ischemia/reperfusion damage, and structural changes in the lung tissue.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.14744/tjtes.2020.70423 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Stress-Free Intubation With Preserved Spontaneous Breathing for Cases With Difficult Airway Management: A Case Series and Retrospective Analysis.
Cureus
August 2025
Anesthesiology, Asahi General Hospital, Asahi, JPN.
Awake tracheal intubation (ATI) is a crucial technique for difficult airway management, particularly in patients with obesity, restricted neck movement, or upper airway abnormalities. Despite its efficacy, ATI is often avoided because of the technical challenges and stress it imposes on patients and anesthesiologists. We describe a new method, termed "intubation maintaining spontaneous breathing with three nerve blocks technique" (3N technique), which leverages nerve blocks to suppress reflexes, preserve spontaneous breathing, and facilitate smooth intubation.
View Article and Find Full Text PDFTracheostomy Cuff Herniation following Cardiac and Pulmonary Arrest.
J Tehran Heart Cent
July 2024
Department of Cardiac Anesthesia, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Tracheostomy is a common procedure performed on patients who require long-term airway maintenance and ventilation support. It is preferred over endotracheal intubation due to its reduced airway resistance, lower risk of displacement compared with the endotracheal tube, increased patient comfort, improved weaning from mechanical ventilation, and enhanced suction capabilities. According to the literature, patients needing airway support for fewer than 12 days can undergo translaryngeal intubation, while tracheostomy is indicated for patients requiring ventilatory support for more than 20 days.
View Article and Find Full Text PDFGerman guidelines for airway management 2023.
Anaesthesiologie
May 2024
Hospital of the Brothers of Mercy Trier, Nordallee 1, 54292, Trier, Germany.
The German airway management guidelines are intended to serve as an orientation and decision-making aid and thus contribute to the optimal care of patients undergoing anesthesiologic- and intensive medical care. As part of the pre-anesthesiologic evaluation, anatomical and physiological indications for difficult mask ventilation and intubation shall be evaluated. This includes the assessment of mouth opening, dental status, mandibular protrusion, cervical spine mobility and existing pathologies.
View Article and Find Full Text PDFCough flows as a criterion for decannulation of autonomously breathing patients with tracheostomy tubes.
Respir Res
March 2024
Department of Respiratory Rehabilitation Center, Beijing Rehabilitation Hospital of Capital Medical University, Beijing, China.
Background: Adequate cough or exsufflation flow can indicate an option for safe tracheostomy decannulation to noninvasive management. Cough peak flow via the upper airways with the tube capped is an outcome predictor for decannulation readiness in patients with neuromuscular impairment. However, this threshold value is typically measured with tracheotomy tube removed, which is not acceptable culturally in China.
View Article and Find Full Text PDFConcomitant Intubation with Minimal Cuffed Tube and Rigid Bronchoscopy for Severe Tracheo-Carinal Obstruction.
J Clin Med
August 2023
Department of Thoracic Surgery, University of Perugia Medical School, Ospedale Santa Maria della Misericordia, 06134 Perugia, Italy.
Background: Our aim was to report on the use of an innovative technique for airway management utilizing a small diameter, short-cuffed, long orotracheal tube for assisting operative rigid bronchoscopy in critical airway obstruction.
Methods: We retrospectively reviewed the clinical data of 36 patients with life-threatening critical airway stenosis submitted for rigid bronchoscopy between January 2008 and July 2021. The supporting ventilatory tube, part of the Translaryngeal Tracheostomy KIT (Fantoni method), was utilized in tandem with the rigid bronchoscope during endoscopic airway reopening.