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Knowing who is where is a common task for many computer vision applications. Most of the literature focuses on one of two approaches: determining who a detected person is (appearance-based re-identification) and collating positions into a list, or determining the motion of a person (spatio-temporal-based tracking) and assigning identity labels based on tracks formed. This paper presents a model fusion approach, aiming towards combining both sources of information together in order to increase the accuracy of determining identity classes for detected people using re-ranking. First, a Sequential k-Means re-identification approach is presented, followed by a Kalman filter-based spatio-temporal tracking approach. A linear weighting approach is used to fuse the outputs from these models together, with modification of the weights using a decay function and a rule-based system to reflect the strengths and weaknesses of the models under different conditions. Preliminary experimental results with two different person detection algorithms on an indoor person tracking dataset show that fusing the appearance and spatio-temporal models significantly increases the overall accuracy of the classification operation.
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http://dx.doi.org/10.3390/jimaging6050027 | DOI Listing |
Biotechnol Lett
September 2025
Department of Chemical Engineering, Hongik University, Sangsu-dong, Mapo-gu, Seoul, 04066, Republic of Korea.
The cell surface display system employs carrier proteins to present target proteins on the outer membrane of cells. This system enables functional proteins to be exposed on the exterior of living cells without cell lysis, allowing direct interaction with the surrounding environment. A major limitation of conventional approaches is the difficulty in displaying large-sized enzymes or antibodies, despite their critical roles in applications requiring functional domains that must remain intact, such as catalytic or antigen-binding sites.
View Article and Find Full Text PDFEur J Med Chem
September 2025
Shanghai Frontiers Science Center of Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai, 200240, China; State Key Laboratory of Innovative Immunotherapy, Central Research Institute,
Overexpression of protein lysine methyltransferase G9a, which catalyzes mono- and di-methylation of histone H3K9 and non-histone proteins, is closely associated with poor prognosis and metastasis of various cancers. Here, we designed and synthesized a series of novel G9a inhibitors bearing 2-tetrahydroisoquinoline substituted quinazoline scaffold. Among them, compound 31 with 2-dioxole fused tetrahydroisoquinoline exhibited the most potent inhibitory effects against G9a with an IC value of 0.
View Article and Find Full Text PDFNeural Netw
September 2025
School of Automation and Intelligent Sensing, Shanghai Jiao Tong University, Shanghai, 200240, China; Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, Shanghai, 200240, China; Institute of Medical Robotics, Shanghai Jiao Tong University, Shanghai, 200240, China.
3D shape defect detection plays an important role in autonomous industrial inspection. However, accurate detection of anomalies remains challenging due to the complexity of multimodal sensor data, especially when both color and structural information are required. In this work, we propose a lightweight inter-modality feature prediction framework that effectively utilizes multimodal fused features from the inputs of RGB, depth and point clouds for efficient 3D shape defect detection.
View Article and Find Full Text PDFRSC Adv
August 2025
Graduate Institute of Pharmacognosy, College of Pharmacy, Taipei Medical University Taipei 110301 Taiwan
This study represents the first report on the secondary metabolites from the soft coral . Nine terpenoids (1-9) were isolated by antidiabetic-guided isolation, including a new xeniaphyllane-type diterpenoid (Sclerohumin O, 1) and a new norcaryophyllene-type sesquiterpenoid (Norsclerohumin P, 6). These compounds feature a distinctive 4/9-fused ring system, which was the first isolated in the genus.
View Article and Find Full Text PDFMol Cells
September 2025
Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea. Electronic address:
Proper subcellular localization of Toll-like receptors (TLRs) is essential for initiating appropriate innate immune responses against pathogens while avoiding self-reactivity. UNC93B1 is known to mediate the intracellular trafficking of nucleotide-sensing TLRs such as TLR9 which undergoes rapid internalization into endolysosomes upon reaching the cell surface. We previously demonstrated that UNC93B1 also facilitates the plasma membrane localization of TLR5, a sensor for bacterial flagellin.
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