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Sedation can induce atelectasis which may cause suboptimal image quality. This study aimed to identify factors associated with the occurrence of atelectasis during sedation for imaging in pediatric patients. Patients < 18 years who had undergone whole-body magnetic resonance imaging (MRI) under sedation with propofol or dexmedetomidine were included in this study. The development of atelectasis was visually and quantitatively assessed by coronal short tau inversion recovery images of the thoracic level. Multivariable logistic regression was performed to identify the independent factors associated with the development of atelectasis. Ninety-one patients were included in the analysis. In the multivariable analysis, administration of supplemental oxygen was the only factor significantly associated with the occurrence of atelectasis (adjusted odds ratio, 4.84; 95% confidence interval, 1.48-15.83; = 0.009). Univariable analysis showed that the use of dexmedetomidine was associated with a lower incidence of atelectasis; however, this could not be verified in the multivariable analysis. Among the pediatric patients who had undergone imaging under sedation, additional oxygen supplementation was the only independent factor associated with atelectasis occurrence. A prospective clinical trial is required to identify the cause-effect relationship between oxygen administration and occurrence of atelectasis during sedation.
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http://dx.doi.org/10.3390/jcm10163598 | DOI Listing |
BMC Pulm Med
August 2025
Department of Cardiothoracic Surgery, Shaoxing Central Hospital, Shaoxing, Zhejiang Province, 312030, China.
Background: Its objective was to use meta-analysis (MA) to methodically assess the impact of perioperative breathing exercises on the postoperative rehabilitation of patients with lung cancer (LC) having radical resection. METHODS: PubMed, and other databases were searched for randomized controlled trials on radical resection of LC combined with perioperative respiratory training from January 1995 to January 2024. After quality assessment, MA was performed using Review Manager 5.
View Article and Find Full Text PDFTrials
August 2025
Queen Mary University of London, London, UK.
Background: Post-operative pulmonary complications (PPCs) are an important source of morbidity and mortality after major abdominal and thoracic surgery. The use of neuromuscular blocking drugs in general anaesthesia is an important risk factor for PPCs. The incomplete reversal of this neuromuscular blockade at the end of surgery leads to residual weakness of respiratory muscles and predisposes to aspiration of pharyngeal contents, hypoventilation, and thus to PPCs such as atelectasis and pneumonia.
View Article and Find Full Text PDFBMC Gastroenterol
August 2025
Department of Surgery, International Medical Center, Jeddah, Saudi Arabia.
Background: The burden of obesity in Saudi Arabia is partly addressed with Laparoscopic Sleeve Gastrectomy (LSG), a bariatric surgical option, but perioperative complications and prolonged hospital stays persist. Enhanced Recovery After Surgery (ERAS) aims to improve postoperative outcomes.
Objectives: To compare the peri-operative LSG outcomes among patients receiving ERAS and conventional bariatric procedures (non-ERAS).
Pathol Res Pract
October 2025
Division of Trauma Surgery, Emergency Surgery & Surgical Critical, Tongji Trauma Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Department of Emergency and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong
Sepsis-induced myopathy is a significant cause of intensive care unit-acquired weakness (ICUAW) and a leading cause of mortality in ICU patients. ICUAW primarily affects the respiratory muscles and limb skeletal muscles, leading to prolonged mechanical ventilation and bedridden periods. This condition increases the risk of complications such as pneumonia, atelectasis, and lower extremity venous thrombosis, thereby impacting patients' quality of life and, in severe cases, jeopardizing their lives.
View Article and Find Full Text PDFJ Cardiothorac Vasc Anesth
July 2025
Department of Anesthesiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, China. Electronic address:
Objective: To evaluate the impact of individualized positive end-expiratory pressure (PEEP) versus fixed PEEP on postoperative pulmonary complications (PPCs), intraoperative oxygenation, and respiratory mechanics in thoracic surgery. One-lung ventilation (OLV) poses potential risks of PPCs. PEEP may mitigate lung injury, but the optimal PEEP level remains uncertain.
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