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This paper works on building an effective massive multi-input multi-output (MIMO) relay system by increasing the achievable sum rate and energy efficiency. First, we design a two-hop massive MIMO relay system instead of a one-hop system to shorten the distance and create a Line-of-Sight (LOS) path between relays. Second, we apply Rician channels between relays in this system. Third, we apply low-resolution Analog-to-Digital Converters (ADCs) at both relays to quantize signals, and apply Amplify-and-Forward (AF) and Maximum Ratio Combining (MRC) to the processed signal at relay R1 and relay R2 correspondingly. Fourth, we use higher-order statistics to derive the closed-form expression of the achievable sum rate. Fifth, we derive the power scaling law and achieve the asymptotic expressions under different power scales. Last, we validate the correctness of theoretical analysis with numerical simulation results and show the superiority of the two-hop relay system over the one-hop relay system. From both closed-form expressions and simulation results, we discover that the two-hop system has a higher achievable sum rate than the one-hop system. Besides, the energy efficiency in the two-hop system is higher than the one-hop system. Moreover, in the two-hop system, when quantization bits q = 4, the achievable sum rate converges. Therefore, deploying low-resolution ADCs can improve the energy efficiency and achieve a fairly considerable achievable sum rate.
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http://dx.doi.org/10.3390/e23081074 | DOI Listing |
Cell Rep
September 2025
Department of Biology, MIT, Cambridge, MA 02139, USA; Department of Brain and Cognitive Sciences, MIT, Cambridge, MA 02139, USA; Picower Institute for Learning and Memory, MIT, Cambridge, MA 02139, USA; Biology of Adversity Project, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Elect
The neural control of breathing is both dynamic and essential, ensuring life-sustaining gas exchange while protecting the respiratory system from harm. Peripheral neurons innervating the respiratory tract exhibit remarkable diversity, continuously relaying sensory feedback to the brain to regulate breathing, trigger protective reflexes such as coughing and sickness behaviors, and even influence emotional states. Understanding this airway-brain axis is especially critical given the increasing global burden of respiratory diseases, as it holds implications for both human health and broader brain-body interactions.
View Article and Find Full Text PDFESMO Open
September 2025
Sarah Cannon Research Institute United Kingdom, London, UK. Electronic address:
Background: Antibody-drug conjugates (ADCs) combine targeted monoclonal antibodies with cytotoxic payloads and are an emerging modality in systemic cancer therapy. Thirteen ADCs are Food and Drug Administration approved, with many more in development. However, design and use remain challenging, with issues including on/off-target toxicity, resistance from prior exposure to payload classes, and optimal target/payload selection.
View Article and Find Full Text PDFInorg Chem
September 2025
College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, Jiangsu 215123, China.
The electrochemical reduction of CO into valuable C products presents a sustainable and efficient strategy for the utilization of CO and long-term renewable energy storage. Yet, enhancing the efficiency of the electrocatalytic CO reduction reaction (eCORR) in aqueous systems remains challenging due to the difficulty in activating both CO and HO molecules. In this study, we focus on water activation generating reactive hydrogen species (*H) to boost C product selectivity.
View Article and Find Full Text PDFJ Pestic Sci
August 2025
Department of Chemistry for Life Sciences and Agriculture, Faculty of Life Sciences, Tokyo University of Agriculture.
Developing new agrochemicals is essential for sustainable agriculture and global food security. Our group focused on natural products that control plant pathogens, conducting synthetic research across three key areas of interest: antimicrobial compounds, phytoalexins, and microbial signaling molecules. We established new methods for producing chiral allylic alcohols as useful synthetic intermediates for natural product synthesis the enantioselective synthesis of antimicrobial agents such as peniciaculins.
View Article and Find Full Text PDFJ Am Chem Soc
September 2025
Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon 34141, South Korea.
Achieving precise regioselectivity in the hydroamination of alkenes is in high demand yet remains a longstanding challenge, particularly when electronically competing β-substituents are present. Here, we report a dual boron/iron catalytic system that enables the unprecedented hydroamidation of α,β-unsaturated esters to exclusively access α-amidated esters under mild conditions. The strategy harnesses the Lewis acidity of B(CF) to rapidly generate reactive silyl ketene acetal intermediates, which are subsequently intercepted by in situ generated iron nitrenoids.
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