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Cognitive theories of posttraumatic stress disorder (PTSD) suggest that intrusive memories result from disrupted information processing during traumatic memory encoding and are characterized by fear, helplessness, and horror at recall. Existing naturalistic studies are limited by the absence of direct comparisons between specific moments that do and do not correspond to intrusive memories. We tested predictions from cognitive theories of PTSD by comparing peritraumatic responses during moments experienced as intrusive memories versus distressing moments of the same traumatic event from the same individual not experienced as intrusive memories. A further comparison was with highly distressing moments experienced during the same event by individuals without intrusive memories. We utilized a psychometrically generated model to distinguish different peritraumatic reactions. Moments experienced as intrusive memories were characterized by higher peritraumatic distress, immobility, cognitive overload, and somatic dissociation when compared both to distressing moments from the same individual that did not intrude and to the most distressing memories of individuals without intrusions. Exploratory analyses indicated that at recall, intrusive memories were characterized by higher levels of primary traumatic emotions such as anxiety, fear, and helplessness in comparison with nonintrusive memories. Findings from this novel naturalistic design support predictions made by cognitive theories of PTSD and have implications for research and preventative interventions targeting intrusive memories. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
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http://dx.doi.org/10.1037/abn0000694 | DOI Listing |
Alzheimers Dement
September 2025
Laboratory of Alzheimer's Neuroimaging and Epidemiology, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
Introduction: Receiving an Alzheimer's disease (AD) diagnosis can be a distressing experience, for both the individual with the condition and the family. This cross-sectional study explored whether the disclosure of AD diagnosis generated post-traumatic stress symptoms (PTSSs) in caregivers and how this affected their psychological well-being.
Methods: Seventy-nine caregivers completed the Impact of Event Scale to assess any PTSSs related to the memory of AD disclosure and clinical scales to assess current psychological distress.
J Trauma Acute Care Surg
September 2025
From the Department of Surgery (C.S.), New York-Presbyterian/Weill-Cornell Medical Center, New York; and Department of Surgery (C.C., J.R., K.M., N.M., R.J.R., R.L., J.B.), Jamaica Hospital Medical Center, Queens, New York.
Background: The American College of Surgeons Committee on Trauma requires that trauma centers have a structured approach to identifying patients at risk for mental health conditions. However, the college does not recommend any specific screening protocol. The Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5) is a validated, 20-question screening instrument used at many trauma centers.
View Article and Find Full Text PDFSynapse
September 2025
School of First Clinical, Ningxia Medical University, Yinchuan, Ningxia, China.
Obsessive-compulsive disorder (OCD) is a chronic and debilitating psychiatric condition characterized by persistent, intrusive thoughts (obsessions) and repetitive ritualistic behaviors (compulsions). Accumulating evidence suggests that individuals with OCD demonstrate marked cognitive impairments, especially in executive function domains, including cognitive flexibility and working memory. Although existing therapeutic approaches (e.
View Article and Find Full Text PDFGen Psychiatr
August 2025
Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Post-traumatic stress disorder (PTSD) is a severe neuropsychiatric disorder characterised by re-experiencing, avoidance and hyperarousal. Memory abnormalities manifested as intrusive thoughts and prolonged distressful emotions are postulated as key roles in PTSD development and persistence. Over the past decades, convergent results from human and animal studies have systematically investigated contributions of the amygdala, hippocampus and medial prefrontal cortex (mPFC) in fear memory processes, including fear acquisition, storage, reconsolidation and extinction.
View Article and Find Full Text PDFSensors (Basel)
August 2025
School of Innovation, Design and Engineering, Mälardalen University, 722 20 Västerås, Sweden.
In cyber-physical systems governed by nonlinear partial differential equations (PDEs), real-time control is often limited by sparse sensor data and high-dimensional system dynamics. Deep reinforcement learning (DRL) has shown promise for controlling such systems, but training DRL agents directly on full-order simulations is computationally intensive. This paper presents a sensor-driven, non-intrusive reduced-order modeling (NIROM) framework called FAE-CAE-LSTM, which combines convolutional and fully connected autoencoders with a long short-term memory (LSTM) network.
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