Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375402PMC
http://dx.doi.org/10.3389/fphar.2021.732622DOI Listing

Publication Analysis

Top Keywords

commentary association
4
association antihypertensive
4
antihypertensive medication
4
medication breast
4
breast cancer
4
cancer systematic
4
systematic review
4
review meta-analysis
4
commentary
1
antihypertensive
1

Similar Publications

Prostate cancer (PC) is notoriously known for exhibiting an immunologically cold phenotype in the tumor immune microenvironment (TIME), leading to the need for interventions to enhance immunotherapy efficacy. Recent findings by Zhao in the identified stromal monoamine oxidase A (MAOA), a key enzyme that degrades monoamine neurotransmitters and plays a role in the neuroendocrine system, as a critical regulator of the immune response to PC. Altering MAOA levels in myofibroblastic cancer-associated fibroblasts, either genetically or pharmacologically, can reprogram PC's TIME to modulate CD8 T cell-mediated cytotoxicity through the WNT5A-Ca²-NFATC1 signaling axis, highlighting the stromal influences on CD8 T cell cytotoxic activity within the TIME.

View Article and Find Full Text PDF

Patients as partners in medical publications: the ISMPP journey of engagement.

Curr Med Res Opin

September 2025

International Society for Medical Publication Professionals (ISMPP), Tarrytown, NY, USA.

Patient engagement (PE) has evolved from an emerging concept to a fundamental ethos underpinning healthcare research and communication. In this commentary, we explore the historical evolution in medical research from patients being participants in clinical trials to becoming integral partners in communicating medical research findings. The progression from "why" to "how" PE should occur represents a fundamental shift in the medical publication landscape.

View Article and Find Full Text PDF